Evidence map›Paper›PMID 34669457›Full record

ArticleJournal of clinical microbiology2022

Viral Culture Confirmed SARS-CoV-2 Subgenomic RNA Value as a Good Surrogate Marker of Infectivity.

Marta Santos Bravo, Carla Berengua, Pilar Marín, Montserrat Esteban, Cristina Rodriguez, Margarita Del Cuerpo, Elisenda Miró, Genoveva Cuesta, Mar Mosquera, Sonsoles Sánchez-Palomino and 3 more

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  10. Review
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  12. SARS-CoV-2 Viral Replication Persists in the Human Lung for Several Weeks after Symptom Onset.American journal of respiratory and critical care medicine · 2024
    Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. SARS-CoV-2 viral load and shedding kinetics.Nature reviews. Microbiology · 2023
    Review
  19. Successful lung transplantation using an allograft from a COVID-19-recovered donor: a potential role for subgenomic RNA to guide organ utilization.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Marta Santos Bravo *Microbiology Department, Hospital Clinic of Barcelonagrid.410458.c, Institute of Global Health of Barcelona (ISGlobal), Barcelona, Spain.
Carla Berengua *Microbiology Department, Hospital de la Santa Creu i Sant Pau, Universitat Autonòma de Barcelona, Barcelona, Spain.ORCID 0000-0001-9963-3809
Pilar MarínMicrobiology Department, Hospital de la Santa Creu i Sant Pau, Universitat Autonòma de Barcelona, Barcelona, Spain.
Montserrat EstebanMicrobiology Department, Hospital de la Santa Creu i Sant Pau, Universitat Autonòma de Barcelona, Barcelona, Spain.
Cristina RodriguezMicrobiology Department, Hospital Clinic of Barcelonagrid.410458.c, Institute of Global Health of Barcelona (ISGlobal), Barcelona, Spain.
Margarita Del CuerpoMicrobiology Department, Hospital de la Santa Creu i Sant Pau, Universitat Autonòma de Barcelona, Barcelona, Spain.
Elisenda MiróMicrobiology Department, Hospital de la Santa Creu i Sant Pau, Universitat Autonòma de Barcelona, Barcelona, Spain.
Genoveva CuestaMicrobiology Department, Hospital Clinic of Barcelonagrid.410458.c, Institute of Global Health of Barcelona (ISGlobal), Barcelona, Spain.
Mar MosqueraMicrobiology Department, Hospital Clinic of Barcelonagrid.410458.c, Institute of Global Health of Barcelona (ISGlobal), Barcelona, Spain.
Sonsoles Sánchez-PalominoAIDS Research Group, Institut D'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Hospital Clinic, University of Barcelona, Barcelona, Spain.
Jordi VilaMicrobiology Department, Hospital Clinic of Barcelonagrid.410458.c, Institute of Global Health of Barcelona (ISGlobal), Barcelona, Spain.ORCID 0000-0002-8025-3926
Núria RabellaMicrobiology Department, Hospital de la Santa Creu i Sant Pau, Universitat Autonòma de Barcelona, Barcelona, Spain.
María Ángeles MarcosMicrobiology Department, Hospital Clinic of Barcelonagrid.410458.c, Institute of Global Health of Barcelona (ISGlobal), Barcelona, Spain.
Hospital de Sant Pau · ESUniversitat Autònoma de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Determining SARS-CoV-2 viral infectivity is crucial for patient clinical assessment and isolation decisions. We assessed subgenomic RNA (sgRNA) as a surrogate marker of SARS-CoV-2 infectivity in SARS-CoV-2-positive reverse transcription PCR (RT-PCR) respiratory samples (

Indexed as

COVID-19SARS-CoV-2BiomarkersHumansReverse TranscriptionRNARNA, ViralBiomarkersRNARNA, ViralCOVID-19infectivitySARS-CoV-2subgenomic RNAviral culture

Identifiers

PMID34669457
PMCPMC8769718
OpenAlexW3207246454

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.