Evidence map›Paper›PMID 34669438›Full record

ArticleApplied and environmental microbiology2022

Isolation and Characterization of Lignocellulose-Degrading

Margaux M Meslé, Rebecca C Mueller, Jesse Peach, Brian Eilers, Brian P Tripet, Brian Bothner, Valérie Copié, Brent M Peyton

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Margaux M MesléThermal Biology Institute, Montana State Universitygrid.41891.35, Bozeman, Montana, USA.ORCID 0000-0003-0985-921X
Rebecca C MuellerThermal Biology Institute, Montana State Universitygrid.41891.35, Bozeman, Montana, USA.
Jesse PeachDepartment of Chemistry and Biochemistry, Montana State Universitygrid.41891.35, Bozeman, Montana, USA.
Brian EilersDepartment of Chemistry and Biochemistry, Montana State Universitygrid.41891.35, Bozeman, Montana, USA.
Brian P TripetDepartment of Chemistry and Biochemistry, Montana State Universitygrid.41891.35, Bozeman, Montana, USA.
Brian BothnerDepartment of Chemistry and Biochemistry, Montana State Universitygrid.41891.35, Bozeman, Montana, USA.ORCID 0000-0003-1295-9609
Valérie CopiéDepartment of Chemistry and Biochemistry, Montana State Universitygrid.41891.35, Bozeman, Montana, USA.ORCID 0000-0002-2778-1463
Brent M PeytonThermal Biology Institute, Montana State Universitygrid.41891.35, Bozeman, Montana, USA.ORCID 0000-0003-0033-0651
Montana State University · US

Funding

Research Core (Developmental Research Project Program)P20GM103474 · NIGMS · MONTANA STATE UNIVERSITY - BOZEMAN · PI Jeffrey Good · 2012 to 2026
$60.0M
Acquisition of a 600 MHz NMR cryoprobe and 600 MHz spectrometer console upgradeS10RR026659 · NCRR · MONTANA STATE UNIVERSITY - BOZEMAN · PI COPIE, VALERIE · 2011 to 2011
$600k
NCRR NIH HHS S10 RR026659NIGMS NIH HHS P20 GM103474
6 · The paper itself

Abstract

The microbial degradation of lignocellulose in natural ecosystems presents numerous biotechnological opportunities, including biofuel production from agricultural waste and feedstock biomass. To explore the degradation potential of specific thermophiles, we have identified and characterized extremophilic microorganisms isolated from hot springs environments that are capable of biodegrading lignin and cellulose substrates under thermoalkaline conditions, using a combination of culturing, genomics, and metabolomics techniques. Organisms that can use lignin and cellulose as a sole carbon source at 60 to 75°C were isolated from sediment slurry of thermoalkaline hot springs (71 to 81°C and pH 8 to 9) of Yellowstone National Park. Full-length 16S rRNA gene sequencing indicated that these isolates were closely related to Geobacillus thermoleovorans. Interestingly, most of these isolates demonstrated biofilm formation on lignin, a phenotype that is correlated with increased bioconversion. Assessment of metabolite level changes in two

Indexed as

GeobacillusLigninBiomassEcosystemParks, RecreationalRNA, Ribosomal, 16SLigninlignocelluloseRNA, Ribosomal, 16Salkaline geothermal springbiodegradationbiofuelligninmetabolomics

Identifiers

PMID34669438
PMCPMC8752141
OpenAlexW3205203088

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.