Evidence map›Paper›PMID 34669274›Full record

ArticleBiomedica : revista del Instituto Nacional de Salud2021

Bacteremia after Bacillus clausii administration for the treatment of acute diarrhea: A case report.

Juan Pablo García, Julián Andrés Hoyos, John Alexander Alzate, Edilberto Cristancho

Abstract readCase Reports
In one paragraph

Article in Biomedica : revista del Instituto Nacional de Salud, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Membrane Vesicles fromInternational journal of molecular sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Juan Pablo GarcíaSemillero de Investigación de Medicina Interna, Universidad Tecnológica de Pereira, Pereira, Colombia. juan.garcia@utp.edu.co.
Julián Andrés HoyosDepartamento de Medicina Interna, Universidad Tecnológica de Pereira, Pereira, Colombia. juanhope9@hotmail.com.
John Alexander AlzateDepartamento de Medicina Interna, Universidad Tecnológica de Pereira, Pereira, Colombia. alexalzatej@gmail.com.
Edilberto CristanchoLaboratorio de Microbiología, Hospital Universitario San Jorge, Pereira, Colombia. edil2690@hotmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacillus clausii is a gram-positive rod used as a probiotic to treat diarrhea and the side effects of antibiotics such as pseudomembranous colitis. We report a case of B. clausii bacteremia in a non-immunocompromised patient with active peptic ulcer disease and acute diarrhea. The probiotic was administered during the patient´s hospitalization due to diarrhea of infectious origin. B. clausii was identified in the bloodstream of the patient through Matrix-Assisted Laser Desorption Ionization-Time of Flight (MALDI-TOF) days after her discharge. Given the wide use of probiotics, we alert clinicians to consider this microorganism as a causative agent when signs of systemic infection, metabolic compromise, and hemodynamic instability establish after its administration and no pathogens have been identified that could explain the clinical course.

Indexed as

Bacillus clausiiBacteremiaProbioticsAnti-Bacterial AgentsDiarrheaFemaleHumansSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationAnti-Bacterial AgentsBacillus clausiibacteremiadiarrheagram-positive bacteriaprobiotics

Identifiers

PMID34669274
PMCPMC8598109

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.