Evidence map›Paper›PMID 34669164›Full record

ArticleInfection2022

Mobile PCR-based surveillance for SARS-CoV-2 to reduce visiting restrictions in nursing homes during the COVID-19 pandemic: a pilot study.

Jannik Stemler, Theresa Kramer, Vassiliki Dimitriou, Ulrike Wieland, Sofie Schumacher, Rosanne Sprute, Max Oberste, Gerhard Wiesmüller, Harald Rau, Sally Pieper and 6 more

Registry-linked trialOpen access · hybridAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04933981 (Mobile PCR-based Surveillance for SARS-CoV-2 to Reduce Visiting Restrictions in Nursing Homes During the COVID-19 Pandemic), which is not on this map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04933981 completednot on this map

Mobile PCR-based Surveillance for SARS-CoV-2 to Reduce Visiting Restrictions in Nursing Homes During the COVID-19 Pandemic

TypeobservationalSponsorUniversity of CologneRan2020 to 2021Enrolled1,587ConditionsCOVID-19 Respiratory Infection, SARS-CoV-2 InfectionArmsNasopharyngeal swab for SARS-CoV-2
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 1 country.

Jannik Stemler *Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Excellence Center for Medical Mycology (ECMM), University of Cologne, Cologne, North Rhine-Westphalia, Germany.ORCID http://orcid.org/0000-0001-9152-2469
Theresa Kramer *Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Excellence Center for Medical Mycology (ECMM), University of Cologne, Cologne, North Rhine-Westphalia, Germany.ORCID http://orcid.org/0000-0001-5187-6510
Vassiliki DimitriouFaculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Excellence Center for Medical Mycology (ECMM), University of Cologne, Cologne, North Rhine-Westphalia, Germany.
Ulrike WielandFaculty of Medicine and University Hospital Cologne, Institute of Virology, University of Cologne, Cologne, North Rhine-Westphalia, Germany.ORCID http://orcid.org/0000-0003-3480-4413
Sofie SchumacherFaculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Excellence Center for Medical Mycology (ECMM), University of Cologne, Cologne, North Rhine-Westphalia, Germany.ORCID http://orcid.org/0000-0002-8805-1421
Rosanne SpruteFaculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Excellence Center for Medical Mycology (ECMM), University of Cologne, Cologne, North Rhine-Westphalia, Germany.ORCID http://orcid.org/0000-0003-2457-6437
Max ObersteFaculty of Medicine and University Hospital Cologne, Institute of Medical Statistics and Computational Biology (IMSB), University of Cologne, Cologne, North Rhine-Westphalia, Germany.ORCID http://orcid.org/0000-0002-1224-5385
Gerhard WiesmüllerDepartment of Public Health, City Council of Cologne, Cologne, North Rhine-Westphalia, Germany.
Harald RauDepartment of Social Affairs, Health and Environment, City Council of Cologne, Cologne, North Rhine-Westphalia, Germany.ORCID http://orcid.org/0000-0001-6681-2288
Sally PieperFaculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Excellence Center for Medical Mycology (ECMM), University of Cologne, Cologne, North Rhine-Westphalia, Germany.
Ullrich BetheFaculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Excellence Center for Medical Mycology (ECMM), University of Cologne, Cologne, North Rhine-Westphalia, Germany.ORCID http://orcid.org/0000-0001-9979-1671
Clara LehmannFaculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, University of Cologne, Cologne, North Rhine-Westphalia, Germany.ORCID http://orcid.org/0000-0002-7042-1578
Martin HellmichFaculty of Medicine and University Hospital Cologne, Institute of Medical Statistics and Computational Biology (IMSB), University of Cologne, Cologne, North Rhine-Westphalia, Germany.ORCID http://orcid.org/0000-0001-5174-928X
Florian KleinFaculty of Medicine and University Hospital Cologne, Institute of Virology, University of Cologne, Cologne, North Rhine-Westphalia, Germany.ORCID http://orcid.org/0000-0003-1376-1792
Georg LangebartelsFaculty of Medicine and University Hospital Cologne, Department for Clinical Affairs and Crisis Management, University of Cologne, Cologne, North Rhine-Westphalia, Germany.
Oliver A CornelyFaculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Excellence Center for Medical Mycology (ECMM), University of Cologne, Cologne, North Rhine-Westphalia, Germany. Oliver.Cornely@uk-koeln.de.ORCID http://orcid.org/0000-0001-9599-3137
University of Cologne · DEStadtwerke Köln (Germany) · DE

Funding

bundesministerium für bildung und forschung 01KX2021
6 · The paper itself

Abstract

purposeResidents in nursing homes for the elderly (NH) are at high risk for death from COVID-19. We investigated whether repeated non-mandatory RT-PCR SARS-CoV-2 surveillance of NH staff and visitors reduces COVID-19 incidence rates in NH residents and allows to reduce visiting restrictions.

methodsThis pilot study at the beginning of the COVID-19 pandemic compared a surveillance approach of regular, twice-weekly voluntary PCR testing of health-care workers (HCW) and visitors in interventional NH (INH) with a setting without regular testing in control NH (CNH). Residents were not tested routinely within this study. Testing was performed in a mobile testing site with same-day result reporting. SARS-CoV-2 incidence among residents in both INH and CNH was the primary endpoint; secondary endpoints being SARS-CoV-2 infection among visitors and HCW in INH.

resultsTwo INH and two CNH participated between October and December, 2020. At INH1, 787 tests of HCW and 350 tests of visitors were performed, accounting for 18.1% (n = 1930) of visits. At INH2, 78 tests of HCW and 372 tests of visitors were done, i.e., 30.5% (n = 1220) of visits. At the two INH 23 HCW and three visitors tested positive for SARS-CoV-2. COVID-19 outbreaks occurred among residents in INH1 (identified through study testing) and in CNH1. Utilization of voluntary testing was low.

conclusionIn a real-world setting without available rapid testing, voluntary RT-PCR SARS-CoV-2 testing of HCW and visitors does not prevent COVID-19 outbreaks in NH. Complete, non-selective testing for these groups should be instituted before visiting restrictions can be reduced.

trial registrationThe study has been registered at ClinicalTrials.gov with the identifier: NCT04933981.

Indexed as

COVID-19SARS-CoV-2AgedCOVID-19 TestingHumansNursing HomesPandemicsPilot ProjectsPolymerase Chain ReactionCOVID-19 pandemicNursing homeSARS-CoV-2 transmissionSurveillanceTesting on site

Identifiers

PMID34669164
PMCPMC8527812
OpenAlexW3207663931

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.