Evidence map›Paper›PMID 34668864›Full record

ArticleEpileptic disorders : international epilepsy journal with videotape2021

Early diagnosis and experimental treatment with fenfluramine via the Investigational New Drug mechanism in a boy with Dravet syndrome and recurrent status epilepticus.

Sara Trowbridge, Annapurna Poduri, Heather Olson

Open access · goldAbstract readCase Reports
In one paragraph

Article in Epileptic disorders : international epilepsy journal with videotape, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Navigating the Intersection of Technology and Depression Precision Medicine.Advances in experimental medicine and biology · 2024
    Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Sara TrowbridgeDivision of Epilepsy and Clinical Neurophysiology and Epilepsy Genetics Program, Department of Neurology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA.
Annapurna PoduriDivision of Epilepsy and Clinical Neurophysiology and Epilepsy Genetics Program, Department of Neurology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA.
Heather OlsonDivision of Epilepsy and Clinical Neurophysiology and Epilepsy Genetics Program, Department of Neurology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA.
Boston Children's Hospital · USHarvard University · US

Funding

Diagnosis and Genotype-Phenotype Correlations in Early Life Epilepsy and CDKL5 DisorderK23NS107646 · NINDS · BOSTON CHILDREN'S HOSPITAL · PI OLSON, HEATHER ELISA · 2018 to 2023
$1.2M
NINDS NIH HHS K23 NS107646
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Epilepsies, MyoclonicEpileptic SyndromesFenfluramineSpasms, InfantileStatus EpilepticusAnticonvulsantsDrugs, InvestigationalEarly DiagnosisHumansMaleAnticonvulsantsDrugs, InvestigationalFenfluramine

Identifiers

PMID34668864
PMCPMC8842495
OpenAlexW3205708892

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.