Evidence map›Paper›PMID 34668776›Full record

ArticleJournal of virology2022

The HIV-1 Matrix Protein p17 Does Cross the Blood-Brain Barrier.

Francesca Caccuri, Vera Neves, Lurdes Gano, João D G Correia, Maria Cristina Oliveira, Pietro Mazzuca, Arnaldo Caruso, Miguel Castanho

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of virology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
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  7. HIV-1 mutants expressing B cell clonogenic matrix protein p17 variants are increasing their prevalence worldwide.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Francesca Caccuri *Department of Molecular and Translational Medicine, University of Bresciagrid.7637.5 Medical School, Brescia, Italy.
Vera Neves *Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal.
Lurdes GanoCentro de Ciências e Tecnologias Nucleares and Departamento de Engenharia e Ciências Nucleares, Instituto Superior Técnico, Universidade de Lisboa, Bobadela, Portugal.
João D G CorreiaCentro de Ciências e Tecnologias Nucleares and Departamento de Engenharia e Ciências Nucleares, Instituto Superior Técnico, Universidade de Lisboa, Bobadela, Portugal.
Maria Cristina OliveiraCentro de Ciências e Tecnologias Nucleares and Departamento de Engenharia e Ciências Nucleares, Instituto Superior Técnico, Universidade de Lisboa, Bobadela, Portugal.
Pietro MazzucaDepartment of Molecular and Translational Medicine, University of Bresciagrid.7637.5 Medical School, Brescia, Italy.
Arnaldo Caruso *Department of Molecular and Translational Medicine, University of Bresciagrid.7637.5 Medical School, Brescia, Italy.ORCID 0000-0001-5178-566X
Miguel Castanho *Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal.
University of Lisbon · PTUniversity of Brescia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human immunodeficiency virus type 1 (HIV-1)-associated neurocognitive disorder (HAND) remains an important neurological manifestation in HIV-1-infected (HIV

Indexed as

Host-Pathogen InteractionsAnimalsAutophagyBlood-Brain BarrierCell LineCells, CulturedDisease SusceptibilityEndosomesEndothelial Cellsgag Gene Products, Human Immunodeficiency VirusHIV-1HIV AntigensHIV InfectionsHumansMiceProtein BindingCXCR2 protein, humangag Gene Products, Human Immunodeficiency VirusHIV Antigensp17 protein, Human Immunodeficiency Virus Type 1Receptors, Interleukin-8Bblood-brain barrierHIV-1 matrix protein p17HIV-associated neurocognitive disorderin vivo biodistributiontranscytosis

Identifiers

PMID34668776
PMCPMC8754207
OpenAlexW3207178943

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.