Evidence map›Paper›PMID 34668721›Full record

ArticleMicrobiology spectrum2021

Semirapid Detection of Piperacillin/Tazobactam Resistance and Extended-Spectrum Resistance to β-Lactams/β-Lactamase Inhibitors in Clinical Isolates of Escherichia coli.

Ángel Rodríguez-Villodres, Alicia Gutiérrez Linares, Lydia Gálvez-Benitez, Jerónimo Pachón, José Antonio Lepe, Younes Smani

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. False equivalence: differences in theJAC-antimicrobial resistance · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ángel Rodríguez-Villodres *Clinical Unit of Infectious Diseases, Microbiology and Preventive Medicine, Hospital Universitario Virgen del Rocío, Seville, Spain.ORCID 0000-0001-6373-9724
Alicia Gutiérrez Linares *Institute of Biomedicine of Sevillegrid.414816.e (IBiS), Hospital Universitario Virgen del Rocío/CSIC/University of Seville, Seville, Spain.
Lydia Gálvez-BenitezClinical Unit of Infectious Diseases, Microbiology and Preventive Medicine, Hospital Universitario Virgen del Rocío, Seville, Spain.
Jerónimo PachónInstitute of Biomedicine of Sevillegrid.414816.e (IBiS), Hospital Universitario Virgen del Rocío/CSIC/University of Seville, Seville, Spain.
José Antonio LepeClinical Unit of Infectious Diseases, Microbiology and Preventive Medicine, Hospital Universitario Virgen del Rocío, Seville, Spain.
Younes SmaniClinical Unit of Infectious Diseases, Microbiology and Preventive Medicine, Hospital Universitario Virgen del Rocío, Seville, Spain.ORCID 0000-0001-9302-8384
Instituto de Biomedicina de Sevilla · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Piperacillin/tazobactam (TZP) is a β-lactam/β-lactamase inhibitor (BL/BLI) recommended for the empirical treatment of severe infections. The excessive and indiscriminate use of TZP has promoted the emergence of TZP-resistant Escherichia coli isolates. Recently, we demonstrated that TZP may contribute to the development of

Indexed as

Drug Resistance, Multiple, BacterialAnti-Bacterial AgentsBacteriological Techniquesbeta-Lactamase Inhibitorsbeta-Lactamasesbeta-LactamsEscherichia coliEscherichia coli InfectionsHumansLactamsMicrobial Sensitivity TestsPiperacillin, Tazobactam Drug CombinationAnti-Bacterial Agentsbeta-Lactamase Inhibitorsbeta-Lactamasesbeta-LactamsLactamsPiperacillin, Tazobactam Drug Combinationbeta-lactamasebeta-lactamase inhibitorEscherichia coliESRIpiperacillinresistancetazobactam

Identifiers

PMID34668721
PMCPMC8528104
OpenAlexW3207411926

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.