Evidence map›Paper›PMID 34668657›Full record

ArticleEndocrinology, diabetes & metabolism2022

Influence of glycaemic control on macular thickness in diabetic retinopathy.

Sadhana Sharma, Pratap Karki, Sagun Narayan Joshi, Sanket Parajuli

Open access · goldAbstract read
In one paragraph

Article in Endocrinology, diabetes & metabolism, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Sadhana SharmaMechi Eye Hospital, Jhapa, Nepal.ORCID 0000-0002-0550-6938
Pratap KarkiDepartment of Retina, B.P Koirala Lions Center for Ophthalmic Studies (BPKLCOS), Institute of Medicine, Kathmandu, Nepal.
Sagun Narayan JoshiDepartment of Retina, B.P Koirala Lions Center for Ophthalmic Studies (BPKLCOS), Institute of Medicine, Kathmandu, Nepal.
Sanket ParajuliReiyukai Eiko Masunaga Eye Hospital, Banepa, Nepal.
B.P. Koirala Institute of Health Sciences · NPTilganga Institute of Ophthalmology · NP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDiabetic macular oedema (DME) is one of the major cause of decreased visual acuity in patients with diabetic retinopathy. Poor glycaemic control is associated with increased incidence of DME.

methodsA total of 112 eyes of 112 patients were studied in this cross-sectional study and were classified into three groups based on HbA1c: group 1 included patients with good glycaemic control (HbA1c ≤7%), group 2 included patients with moderate glycaemic control (HbA1c between 7% and 9%) and group 3 included patients with poor glycaemic control (HbA1c ≥9%).

resultsWe included 112 eyes of 112 patients. The mean duration of diabetes mellitus (DM) was 11.37 years. In statistical analysis, CMT (mean 188.80 ± 27.64 μm) positively correlated with mean HbA1c level (7.95 ± 1.29%) (r = 0.238, p < .05). There was a significant difference in CMT values among the three groups of HbA1c (F (2,109) = 19.39, p < .001). Post hoc analysis showed statistical significance between HbA1c≤7% and HbA1c ≥9% group and HbA1c 7%-9% and ≥9% group. However, statistical significance was not found among HbA1c ≤7% group and HbA1c 7%-9% group. Multiple regression analyses showed a significant correlation between CMT and HbA1c after adjusting for age and duration of diabetes.

conclusionSerum HbA1c level has a significant correlation with CMT in diabetic patients.

Indexed as

Diabetes MellitusDiabetic RetinopathyCross-Sectional StudiesGlycemic ControlHumansTomography, Optical CoherenceVisual Acuitycentral macular thicknessdiabetic macular oedemaHbA1c

Identifiers

PMID34668657
PMCPMC8754239
OpenAlexW3205033983

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.