Evidence map›Paper›PMID 34668636›Full record

ArticleMolecular oncology2022

Metastatic colorectal cancer and type 2 diabetes: prognostic and genetic interactions.

Alessandro Ottaiano, Luisa Circelli, Mariachiara Santorsola, Giovanni Savarese, Daniela Fontanella, Valerio Gigantino, Annabella Di Mauro, Maurizio Capuozzo, Silvia Zappavigna, Angela Lombardi and 6 more

Open access · goldAbstract read
In one paragraph

Article in Molecular oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

Alessandro OttaianoIstituto Nazionale Tumori di Napoli, IRCCS "G. Pascale,", Naples, Italy.ORCID 0000-0002-2901-3855
Luisa CircelliAMES, Centro Polidiagnostico Strumentale srl, Naples, Italy.
Mariachiara SantorsolaIstituto Nazionale Tumori di Napoli, IRCCS "G. Pascale,", Naples, Italy.
Giovanni SavareseAMES, Centro Polidiagnostico Strumentale srl, Naples, Italy.
Daniela FontanellaMolecular Biology, Innovalab Scarl, Naples, Italy.
Valerio GigantinoMolecular Biology, Innovalab Scarl, Naples, Italy.
Annabella Di MauroIstituto Nazionale Tumori di Napoli, IRCCS "G. Pascale,", Naples, Italy.
Maurizio CapuozzoMolecular Biology, Innovalab Scarl, Naples, Italy.
Silvia ZappavignaDepartment of Precision Medicine, University "L. Vanvitelli" of Naples, Italy.
Angela LombardiDepartment of Precision Medicine, University "L. Vanvitelli" of Naples, Italy.
Francesco PerriIstituto Nazionale Tumori di Napoli, IRCCS "G. Pascale,", Naples, Italy.
Marco CascellaIstituto Nazionale Tumori di Napoli, IRCCS "G. Pascale,", Naples, Italy.
Vincenza GranataIstituto Nazionale Tumori di Napoli, IRCCS "G. Pascale,", Naples, Italy.
Maurizio CapuozzoDepartment of Pharmacy, ASL-Naples-3, Ercolano, Italy.
Guglielmo NastiIstituto Nazionale Tumori di Napoli, IRCCS "G. Pascale,", Naples, Italy.
Michele CaragliaDepartment of Precision Medicine, University "L. Vanvitelli" of Naples, Italy.ORCID 0000-0003-2408-6091
Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale" · ITInnova (Italy) · ITUniversity of Campania "Luigi Vanvitelli" · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study was undertaken to analyze prognostic and genetic interactions between type 2 diabetes and metastatic colorectal cancer. Patients' survival was depicted through the Kaplan-Meier product limit method. Prognostic factors were examined through the Cox proportional-hazards regression model, and associations between diabetes and clinical-pathologic variables were evaluated by the χ

Indexed as

Neoplasm MetastasisAgedColorectal NeoplasmsDiabetes Mellitus, Type 2FemaleGenotypeHumansKaplan-Meier EstimateMaleMiddle AgedPhenotypePrognosisgenesmetastatic colorectal canceroligo-metastatic colorectal cancerprognosissurvivaltype 2 diabetes

Identifiers

PMID34668636
PMCPMC8763648
OpenAlexW3205791011

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.