Evidence map›Paper›PMID 34668629›Full record

ArticleAustralasian journal on ageing2022

Risk factors for myocardial injury at admission of 325 patients with coronavirus disease 2019 in Shanghai, China.

Xue Mei, Yuanyuan Ji, Zhiping Qian, Yun Ling, Hui Zhu, Xingcheng Zhao, Fang Shen, Qingnian Xu, Zhengguo Zhang, Xingxia Cheng and 7 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Australasian journal on ageing, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 1 institution in 1 country.

Xue MeiDepartment of Severe Hepatology, Shanghai Public Health Clinical Centre, Fudan University, Shanghai, China.
Yuanyuan JiDepartment of Hepatology, Shanghai Public Health Clinical Centre, Fudan University, Shanghai, China.
Zhiping QianDepartment of Severe Hepatology, Shanghai Public Health Clinical Centre, Fudan University, Shanghai, China.
Yun LingDepartment of Infection Disease, Shanghai Public Health Clinical Centre, Fudan University, Shanghai, China.
Hui ZhuDepartment of Severe Hepatology, Shanghai Public Health Clinical Centre, Fudan University, Shanghai, China.
Xingcheng ZhaoDepartment of Orthopedics, Shanghai Public Health Clinical Centre, Fudan University, Shanghai, China.
Fang ShenDepartment of Functional Inspection, Shanghai Public Health Clinical Centre, Fudan University, Shanghai, China.
Qingnian XuDepartment of Traditional Chinese Medicine, Shanghai Public Health Clinical Centre, Fudan University, Shanghai, China.
Zhengguo ZhangDepartment of Severe Hepatology, Shanghai Public Health Clinical Centre, Fudan University, Shanghai, China.
Xingxia ChengDepartment of Severe Hepatology, Shanghai Public Health Clinical Centre, Fudan University, Shanghai, China.
Yu LiuDepartment of Severe Hepatology, Shanghai Public Health Clinical Centre, Fudan University, Shanghai, China.
Hongying GuoDepartment of Severe Hepatology, Shanghai Public Health Clinical Centre, Fudan University, Shanghai, China.
Ying ZouDepartment of Severe Hepatology, Shanghai Public Health Clinical Centre, Fudan University, Shanghai, China.
Jiefei WangDepartment of Severe Hepatology, Shanghai Public Health Clinical Centre, Fudan University, Shanghai, China.
Yuyi ZhangDepartment of Severe Hepatology, Shanghai Public Health Clinical Centre, Fudan University, Shanghai, China.
Lie XuDepartment of Infection Disease, Shanghai Public Health Clinical Centre, Fudan University, Shanghai, China.
Hongzhou LuDepartment of Infection and Immunology, Shanghai Public Health Clinical Centre, Fudan University, Shanghai, China.ORCID https://orcid.org/0000-0002-8308-5534
Shanghai Public Health Clinical Center · CN

Funding

the scientific research project on the novel coronavirus "2019-nCoV" from the Shanghai Public Health Clinical Centre 2020YJKY01the Top University and First-class Discipline Construction Project of Fudan University IDF162005The Top University and First-class Discipline Construction Project of Fudan University IDF162005
6 · The paper itself

Abstract

objectiveMyocardial injury leads to higher mortality in COVID-19, but the causes and risk factors are variable. We evaluated the potential risk factors for myocardial injury in COVID-19 patients to improve treatment strategies and reduce mortality.

methodsThis retrospective analysis enrolled 325 COVID-19 patients in Shanghai, China.

resultsThe median age in our cohort was 51 [range 15-88] years, 26 (8%) were critically ill, and 177 patients (19.7%) had myocardial injury. The myocardial injury group comprised older, more critically ill patients with hypertension, other comorbidities, history of angiotensin-converting enzyme inhibitor/angiotensin receptor blocker use, lower peripheral blood lymphocyte count and higher D-dimer levels. Binary logistic regression analysis identified only age was an independent risk factor for myocardial injury (odds ratio 1.019; 95% confidence interval 1.003-1.036; age increase by 1 year = myocardial injury risk increase by 1.9%).

conclusionsOlder age was associated with a higher incidence of myocardial injury for COVID-19 patients.

Indexed as

COVID-19AgedAged, 80 and overChinaHumansRetrospective StudiesRisk FactorsSARS-CoV-2COVID-19myocardial injurynovel coronavirus pneumoniaSARS-CoV-2

Identifiers

PMID34668629
PMCPMC8646350
OpenAlexW3205661410

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.