ArticlePediatric transplantation2022
Acute kidney disease predicts chronic kidney disease in pediatric non-kidney solid organ transplant patients.
Article in Pediatric transplantation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.
- Growth after pediatric and neonatal acute kidney injury: a meta-analysis.Pediatric nephrology (Berlin, Germany) · 2025Pooled it
- Risk Factors and Outcomes Associated With the Development of Persistent Acute Kidney Injury in Non-Renal Solid Organ Transplant Recipients: Systematic Review and Meta-Analysis.Clinical transplantation · 2024Pooled it
- Time Course of Kidney Injury Biomarkers in Children With Septic Shock: Nested Cohort Study Within the Pragmatic Pediatric Trial of Balanced Versus Normal Saline Fluid in Sepsis Trial.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2025Trial
- Improving pediatric post-acute kidney injury care: considerations for the clinician.Renal failure · 2026Review
- Acute kidney diseases and disorders in children with bloodstream infection: frequency, predictors, and outcomes.Pediatric nephrology (Berlin, Germany) · 2026Article
- Perioperative anesthetic management in pediatric heart transplantation: a single-center descriptive study involving 27 patients.Frontiers in pediatrics · 2026Article
- An innocent bystander or a predisposing culprit? Kidney injury following pediatric liver transplantation.Pediatric nephrology (Berlin, Germany) · 2025Article
- Optimizing kidney health following pediatric liver transplantation: current challenges and future directions.Pediatric nephrology (Berlin, Germany) · 2025Article
- Outcomes of acute kidney injury continuum in children.Journal of nephrology · 2024Article
- Acute Kidney Injury Requiring Dialysis After Pediatric Heart Transplant.Pediatric transplantation · 2024Article
- Acute Kidney Disease following Acute Kidney Injury in Children-A Retrospective Observational Cohort Study on Risk Factors and Outcomes.Journal of clinical medicine · 2024Article
- A reappraisal of risk factors for hypertension after pediatric acute kidney injury.Pediatric nephrology (Berlin, Germany) · 2024Observational
- Patient level factors increase risk of acute kidney disease in hospitalized children with acute kidney injury.Pediatric nephrology (Berlin, Germany) · 2023Article
- Kinetic Estimated Glomerular Filtration Rate in Predicting Paediatric Acute Kidney Disease.Journal of clinical medicine · 2023Article
- Etiology and outcomes of acute kidney disease in children: a cohort study.Clinical and experimental nephrology · 2023Article
- Update on prognosis driven classification of pediatric AKI.Frontiers in pediatrics · 2022Review
- Acute Kidney Disease in Hospitalized Pediatric Patients With Acute Kidney Injury in China.Frontiers in pediatrics · 2022Article
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9 authors at 5 institutions in 2 countries.
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Abstract
backgroundAcute kidney disease (AKD) is defined as impaired kidney function present for <90 days with or without an acute kidney injury (AKI) event. Adults with AKD have an increased risk for progression to chronic kidney disease (CKD) and mortality. There are no data on the epidemiology of AKD in children after transplant. The aim of this study was to evaluate the incidence and risk factors for AKI, AKD, and CKD in children after transplantation.
methodsThis is a retrospective cohort study of all children undergoing non-kidney solid organ transplant between 2011 and 2019 at UPMC Children's Hospital of Pittsburgh. AKI and AKD were defined using the Kidney Disease Improving Global Outcomes criteria. Patients with a new estimated glomerular filtration rate <60 ml/min/1.73m
resultsAmong 338 patients, 37.9% met criteria for severe AKI, 13% for AKD, and 8% for a new diagnosis of CKD. Stage 3 AKI was independently associated with AKD (OR: 5.35; 95% CI: 2.23-12.86). Severe AKI was not associated with new-onset CKD, whereas AKD was associated with new-onset CKD (OR: 29.74; CI: 11.22-78.82).
conclusionAKD may be superior to AKI in predicting risk of CKD in children after non-kidney solid organ transplantation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.