ArticleCerebral cortex (New York, N.Y. : 1991)2022
Brain Responses to Surprising Stimulus Offsets: Phenomenology and Functional Significance.
Article in Cerebral cortex (New York, N.Y. : 1991), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed.
- Gaboxadol increases resting theta and alpha power without affecting evoked responses in fragile X syndrome in a home-based setting.Journal of neurodevelopmental disorders · 2026Trial
- A two-system theory of sensory-evoked brain responses.Brain : a journal of neurology · 2026Review
- Conceptual rethinking of whole-body perturbation-evoked potentials as a biomarker of extralemniscal sensory transmission, alertness and arousal.Frontiers in human neuroscience · 2026Article
- Behavior-Relevant Periodized Neural Representation of Acoustic But Not Tactile Rhythm in Humans.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- The Extralemniscal System Modulates Early Somatosensory Cortical Processing.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Sensing What You Do Not See: Alerting of Approaching Objects with a Haptic Vest.Sensors (Basel, Switzerland) · 2025Article
- Hyper-extralemniscal model of Fragile X syndrome.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- Healthy aging is associated with altered visual gamma band onset and offset responses.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- A Cortical Mechanism Linking Saliency Detection and Motor Reactivity in Rhesus Monkeys.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Article
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Authors and funding
7 authors.
Funding
Abstract
Abrupt increases of sensory input (onsets) likely reflect the occurrence of novel events or objects in the environment, potentially requiring immediate behavioral responses. Accordingly, onsets elicit a transient and widespread modulation of ongoing electrocortical activity: the Vertex Potential (VP), which is likely related to the optimisation of rapid behavioral responses. In contrast, the functional significance of the brain response elicited by abrupt decreases of sensory input (offsets) is more elusive, and a detailed comparison of onset and offset VPs is lacking. In four experiments conducted on 44 humans, we observed that onset and offset VPs share several phenomenological and functional properties: they (1) have highly similar scalp topographies across time, (2) are both largely comprised of supramodal neural activity, (3) are both highly sensitive to surprise and (4) co-occur with similar modulations of ongoing motor output. These results demonstrate that the onset and offset VPs largely reflect the activity of a common supramodal brain network, likely consequent to the activation of the extralemniscal sensory system which runs in parallel with core sensory pathways. The transient activation of this system has clear implications in optimizing the behavioral responses to surprising environmental changes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.