Evidence map›Paper›PMID 34668483›Full record

ArticleeLife2021

Disturbed retinoid metabolism upon loss of

Domino K Schlegel, Srinivasagan Ramkumar, Johannes von Lintig, Stephan Cf Neuhauss

Abstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Germline Disruption of Retinal Pigment Epithelium-Expressed Zebrafish rlbp1bFASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Vitamin A supply in the eye and establishment of the visual cycle.Current topics in developmental biology · 2025
    Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. An Overview towards Zebrafish Larvae as a Model for Ocular Diseases.International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Domino K SchlegelDepartment of Molecular Life Sciences, University of Zurich, Zürich, Switzerland.ORCID 0000-0001-6194-4695
Srinivasagan RamkumarDepartment of Pharmacology, School of Medicine, Case Western Reserve University, Cleveland, United States.
Johannes von LintigDepartment of Pharmacology, School of Medicine, Case Western Reserve University, Cleveland, United States.
Stephan Cf NeuhaussDepartment of Molecular Life Sciences, University of Zurich, Zürich, Switzerland.ORCID 0000-0002-9615-480X

Funding

Carotinoids in VisionR01EY020551 · NEI · CASE WESTERN RESERVE UNIVERSITY · PI VON LINTIG, JOHANNES FRIEDRICH · 2011 to 2024
$4.8M
STRA6 and Ocular Vitamin A HomeostasisR01EY028121 · NEI · CASE WESTERN RESERVE UNIVERSITY · PI Johannes Friedrich von Lintig · 2018 to 2026
$4.3M
NEI NIH HHS R01 EY020551NEI NIH HHS R01 EY028121
6 · The paper itself

Abstract

The

Indexed as

AnimalsCarrier ProteinsDisease Models, AnimalEpendymoglial CellsLipid MetabolismRetinaRetinal Cone Photoreceptor CellsRetinal DiseasesRetinal Pigment EpitheliumRetinal Rod Photoreceptor CellsRetinoidsZebrafishCarrier ProteinsRetinoidsCRALBPneuroscienceretinal degenerationretinoidvisual cyclezebrafish

Identifiers

PMID34668483
PMCPMC8585484

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.