Evidence map›Paper›PMID 34668464›Full record

ArticleEpidemiology and infection2021

Charting elimination in the pandemic: a SARS-CoV-2 serosurvey of blood donors in New Zealand.

Lauren H Carlton, Tiffany Chen, Alana L Whitcombe, Reuben McGregor, Greg Scheurich, Campbell R Sheen, James M Dickson, Chris Bullen, Annie Chiang, Daniel J Exeter and 4 more

Abstract read
In one paragraph

Article in Epidemiology and infection, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The Advantages of the Zero-COVID-19 Strategy.International journal of environmental research and public health · 2022
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Lauren H CarltonSchool of Medical Sciences, The University of Auckland, Auckland, New Zealand.
Tiffany ChenSchool of Medical Sciences, The University of Auckland, Auckland, New Zealand.
Alana L WhitcombeSchool of Medical Sciences, The University of Auckland, Auckland, New Zealand.
Reuben McGregorSchool of Medical Sciences, The University of Auckland, Auckland, New Zealand.
Greg ScheurichThe New Zealand Blood Service, Auckland, New Zealand.
Campbell R SheenCallaghan Innovation, Christchurch, New Zealand.
James M DicksonSchool of Biological Sciences, The University of Auckland, Auckland, New Zealand.
Chris BullenSchool of Population Health, The University of Auckland, Auckland, New Zealand.
Annie ChiangSchool of Population Health, The University of Auckland, Auckland, New Zealand.
Daniel J ExeterSchool of Population Health, The University of Auckland, Auckland, New Zealand.
Janine PaynterSchool of Population Health, The University of Auckland, Auckland, New Zealand.
Michael G BakerDepartment of Public Health, University of Otago, Wellington, New Zealand.
Richard CharlewoodThe New Zealand Blood Service, Auckland, New Zealand.
Nicole J MorelandSchool of Medical Sciences, The University of Auckland, Auckland, New Zealand.ORCID 0000-0001-6548-637X

Funding

Ministry for Business Innovation and Employment CIAF 0230-AULX1904School of Medicine Foundation (University of Auckland) 3721662
6 · The paper itself

Abstract

New Zealand has a strategy of eliminating SARS-CoV-2 that has resulted in a low incidence of reported coronavirus-19 disease (COVID-19). The aim of this study was to describe the spread of SARS-CoV-2 in New Zealand via a nationwide serosurvey of blood donors. Samples (n = 9806) were collected over a month-long period (3 December 2020-6 January 2021) from donors aged 16-88 years. The sample population was geographically spread, covering 16 of 20 district health board regions. A series of Spike-based immunoassays were utilised, and the serological testing algorithm was optimised for specificity given New Zealand is a low prevalence setting. Eighteen samples were seropositive for SARS-CoV-2 antibodies, six of which were retrospectively matched to previously confirmed COVID-19 cases. A further four were from donors that travelled to settings with a high risk of SARS-CoV-2 exposure, suggesting likely infection outside New Zealand. The remaining eight seropositive samples were from seven different district health regions for a true seroprevalence estimate, adjusted for test sensitivity and specificity, of 0.103% (95% confidence interval, 0.09-0.12%). The very low seroprevalence is consistent with limited undetected community transmission and provides robust, serological evidence to support New Zealand's successful elimination strategy for COVID-19.

Indexed as

AdolescentAdultAgedAged, 80 and overAlgorithmsAntibodies, ViralBlood DonorsCOVID-19COVID-19 Serological TestingDisease EradicationFemaleHumansMaleMiddle AgedNew ZealandPrevalenceAntibodies, ViralCOVID-19eliminationNew Zealandreceptor binding domainSARS-CoV-2seroprevalenceserosurveySpike

Identifiers

PMID34668464
PMCPMC8365046

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.