Evidence map›Paper›PMID 34668394›Full record

ArticleJournal of the American Heart Association2021

Association Between Sleep Disturbances With Neurodevelopmental Problems and Decreased Health-Related Quality of Life in Children With Fontan Circulation.

Kirstin Knobbe, Meghana Partha, Michael D Seckeler, Scott Klewer, Chiu-Hsieh Hsu, Jamie Edgin, Wayne J Morgan, Natalie Provencio-Dean, Silvia Lopez, Sairam Parthasarathy and 1 more

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kirstin KnobbeUAHS Center for Sleep & Circadian Sciences University of Arizona Tucson AZ.
Meghana ParthaUAHS Center for Sleep & Circadian Sciences University of Arizona Tucson AZ.ORCID 0000-0002-8352-0532
Michael D SeckelerDepartment of Pediatrics University of Arizona Tucson AZ.ORCID 0000-0001-9013-5723
Scott KlewerDepartment of Pediatrics University of Arizona Tucson AZ.ORCID 0000-0003-4266-5740
Chiu-Hsieh HsuMel and Enid Zuckerman College of Public Health University of Arizona Tucson AZ.
Jamie EdginDepartment of Psychology University of Arizona Tucson AZ.
Wayne J MorganDepartment of Pediatrics University of Arizona Tucson AZ.
Natalie Provencio-DeanUAHS Center for Sleep & Circadian Sciences University of Arizona Tucson AZ.
Silvia LopezUAHS Center for Sleep & Circadian Sciences University of Arizona Tucson AZ.
Sairam ParthasarathyUAHS Center for Sleep & Circadian Sciences University of Arizona Tucson AZ.
Daniel CombsUAHS Center for Sleep & Circadian Sciences University of Arizona Tucson AZ.ORCID 0000-0003-3821-3629

Funding

ACTIV Integration of Host-targeting Therapies for COVID-19 Administrative Coordinating CenterOT2HL156812 · NHLBI · RESEARCH TRIANGLE INSTITUTE · PI NOLEN, TRACY L, THOMAS, SONIA M · 2020 to 2024
$1270.7M
Pediatric Heart network DCCU10HL068270 · NHLBI · NEW ENGLAND RESEARCH INSTITUTES, INC. · PI MILLER, JULIE ELAINE, TRACHTENBERG, FELICIA LYNN · 2011 to 2016
$44.9M
Ventricular Volumes and Varability (VVV)U01HL068270 · NHLBI · NEW ENGLAND RESEARCH INSTITUTES, INC. · PI SLEEPER, LYNN A · 2001 to 2010
$40.3M
Translational Approaches to Health Disparities in Lung, Sleep, and PandemicsR25HL126140 · NHLBI · UNIVERSITY OF ARIZONA · PI FRANCISCO A MORENO, JANKO Z. NIKOLICH · 2014 to 2026
$4.6M
Pediatric Heart Network: Follow-up of the Single Ventricle Reconstruction TrialU01HL068290 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI LAI, WYMAN W · 2001 to 2010
$4.1M
Pediatric Heart Disease Network: CHOP MembershipU01HL068279 · NHLBI · CHILDREN'S HOSP OF PHILADELPHIA · PI VETTER, VICTORIA L · 2001 to 2010
$3.7M
Randomized Therapeutic Trials in Pediatric Heart DiseaseU01HL068285 · NHLBI · CHILDREN'S HOSPITAL BOSTON · PI NEWBURGER, JANE W. · 2001 to 2010
$3.4M
Randomized Clinical Trials for Pediatric Heart DiseaseU01HL068281 · NHLBI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI SAUL, J PHILIP · 2001 to 2010
$3.2M
Clinical and genomic responses to remote ischemic preconditioningU01HL068288 · NHLBI · HOSPITAL FOR SICK CHLDRN (TORONTO) · PI MCCRINDLE, BRIAN W · 2001 to 2010
$3.0M
Intermountain Pediatric Heart Disease Research CenterU01HL068292 · NHLBI · UNIVERSITY OF UTAH · PI MINICH, L. LUANN · 2001 to 2010
$2.7M
The Duke-UNC-CH Pediatric Cardiology Clinical CenterU01HL068269 · NHLBI · DUKE UNIVERSITY · PI LI, JENNIFER S · 2001 to 2010
$2.6M
Medications for Obstructive Sleep Apnea to Improve Cognition in Children with Down Syndrome (MOSAIC DS)R33HL151254 · NHLBI · UNIVERSITY OF ARIZONA · PI COMBS, DANIEL · 2022 to 2025
$1.3M
NHLBI NIH HHS OT2 HL156812NHLBI NIH HHS R25 HL126140NHLBI NIH HHS R33 HL151254NHLBI NIH HHS R61 HL151254NHLBI NIH HHS U01 HL068269NHLBI NIH HHS U01 HL068270NHLBI NIH HHS U01 HL068279NHLBI NIH HHS U01 HL068281NHLBI NIH HHS U01 HL068285NHLBI NIH HHS U01 HL068288NHLBI NIH HHS U01 HL068290NHLBI NIH HHS U01 HL068292NHLBI NIH HHS U10 HL068270
6 · The paper itself

Abstract

Background Children with Fontan circulation are known to be at increased risk for neurodevelopmental problems and decreased health-related quality of life (HRQOL), but many factors that may contribute to this risk are unknown. Sleep disturbances may be one previously unidentified factor that contributes to this risk. Methods and Results We analyzed data from the Pediatric Heart Network Fontan cross-sectional study to evaluate associations between a parent or child report of sleep disturbance with reported neurodevelopmental concerns and HRQOL in 558 children with Fontan circulation. Parent-reported sleep disturbance was present in 11% of participants and child-reported sleep disturbance was present in 15%. Parent-reported sleep disturbance was associated with a significantly higher risk of attention problems, anxiety, depression, behavioral problems, and developmental delay (

Indexed as

Fontan ProcedureSleep Wake DisordersChildCross-Sectional StudiesHumansQuality of LifeSleepSurveys and Questionnairescognitive impairmentFontan procedurequality of lifesingle ventriclesleep

Identifiers

PMID34668394
PMCPMC8751823

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.