Evidence map›Paper›PMID 34668313›Full record

ArticleCytometry. Part A : the journal of the International Society for Analytical Cytology2021

OMIP-079: Cell cycle of CD4

Ambra Natalini, Sonia Simonetti, Gabriele Favaretto, Giovanna Peruzzi, Fabrizio Antonangeli, Angela Santoni, Miguel Muñoz-Ruiz, Adrian Hayday, Francesca Di Rosa

Open access · greenAbstract read
In one paragraph

Article in Cytometry. Part A : the journal of the International Society for Analytical Cytology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. CD8 + T Cells in Gastrointestinal Cancer: a Perspective on Targeting MicroRNA.Journal of molecular medicine (Berlin, Germany) · 2025
    Review
  10. Article
  11. Article
  12. The High-Affinity IL-2 Receptor Affects White Matter Damage after Cerebral Ischemia by Regulating CD8 + T Lymphocyte Differentiation.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2025
    Article
  13. Frontiers in oncology · 2025
    Article
  14. Review
  15. IL-7Rα on CD4Journal of neuroinflammation · 2024
    Article
  16. Article
  17. OMIP-099: 31-color spectral flow cytometry panel to investigate the steady-state phenotype of human T cells.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2024
    Article
  18. Article
  19. Article
  20. OMIP-095: 40-Color spectral flow cytometry delineates all major leukocyte populations in murine lymphoid tissues.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Ambra NataliniInstitute of Molecular Biology and Pathology, National Research Council of Italy (CNR), Rome, Italy.
Sonia SimonettiInstitute of Molecular Biology and Pathology, National Research Council of Italy (CNR), Rome, Italy.
Gabriele FavarettoInstitute of Molecular Biology and Pathology, National Research Council of Italy (CNR), Rome, Italy.
Giovanna PeruzziCenter for Life Nano- & Neuro-Science, Fondazione Istituto Italiano di Tecnologia (IIT), Rome, Italy.
Fabrizio AntonangeliInstitute of Molecular Biology and Pathology, National Research Council of Italy (CNR), Rome, Italy.
Angela SantoniDepartment of Molecular Medicine, University of Rome "Sapienza", Rome, Italy.
Miguel Muñoz-RuizImmunosurveillance Laboratory, The Francis Crick Institute, London, UK.
Adrian HaydayImmunosurveillance Laboratory, The Francis Crick Institute, London, UK.
Francesca Di RosaInstitute of Molecular Biology and Pathology, National Research Council of Italy (CNR), Rome, Italy.ORCID 0000-0003-0252-9138
Institute of Molecular Biology and Pathology · ITItalian Institute of Technology · ITKing's College London · GBSapienza University of Rome · ITThe Francis Crick Institute · GB

Funding

Consiglio Nazionale delle Ricerche STM-2019Italian Minister of Research and University (MIUR) 2017K55HLC
6 · The paper itself

Abstract

A multicolor flow cytometry panel was designed and optimized to define the following nine mouse T cell subsets: Treg (CD3

Indexed as

SpleenT-Lymphocytes, RegulatoryAnimalsCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCell CycleImmunologic MemoryL-SelectinMemory T CellsMiceMice, Inbred C57BLT-Lymphocyte SubsetsL-Selectincell cycleDNA contentflow cytometryKi-67mouse T cellsspleen

Identifiers

PMID34668313
PMCPMC9543383
OpenAlexW3207755559

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.