Evidence map›Paper›PMID 34668295›Full record

ArticleJournal of thrombosis and haemostasis : JTH2021

Pathologically stiff erythrocytes impede contraction of blood clots: Reply to comment.

Valerie Tutwiler, Rustem I Litvinov, Anna Protopopova, Chandrasekaran Nagaswami, Carlos Villa, Eric Woods, Osheiza Abdulmalik, Don L Siegel, J Eric Russell, Vladimir R Muzykantov and 3 more

Abstract readLetterComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of thrombosis and haemostasis : JTH, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Valerie TutwilerDepartment of Cell and Developmental Biology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.ORCID 0000-0003-1213-4447
Rustem I LitvinovDepartment of Cell and Developmental Biology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.ORCID 0000-0003-0643-1496
Anna ProtopopovaDepartment of Cell and Developmental Biology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Chandrasekaran NagaswamiDepartment of Cell and Developmental Biology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Carlos VillaDepartment of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Eric WoodsMax-Planck-Institut für Eisenforschung GmbH Düsseldorf, Düsseldorf, Germany.
Osheiza AbdulmalikChildren's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Don L SiegelDepartment of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
J Eric RussellDepartment of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Vladimir R MuzykantovDepartment of Pharmacology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Wilbur A LamThe Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia, USA.ORCID 0000-0002-0325-7990
David R MyersThe Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia, USA.
John W WeiselDepartment of Cell and Developmental Biology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-9628-257X

Funding

TRANSFUSION MEDICINE RESEARCH TRAINING PROGRAMT32HL007775 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI SIEGEL, DONALD LAWRENCE · 1993 to 2023
$2.8M
BC-mediated delivery of thromboprophylaxisR01HL159256 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI MUZYKANTOV, VLADIMIR R · 2021 to 2024
$2.6M
NHLBI NIH HHS R01 HL159256NHLBI NIH HHS T32 HL007775
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ThrombosisErythrocytesHumansblood clottingclot contractionerythrocytessickle cell diseasethrombosis

Identifiers

PMID34668295
PMCPMC10031937

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.