Evidence map›Paper›PMID 34668219›Full record

ReviewEnvironmental toxicology and chemistry2022

Changes in Sewage Sludge Chemical Signatures During a COVID-19 Community Lockdown, Part 1: Traffic, Drugs, Mental Health, and Disinfectants.

Sara L Nason, Elizabeth Lin, Brian Eitzer, Jeremy Koelmel, Jordan Peccia

Abstract readReview
In one paragraph

Review in Environmental toxicology and chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sara L NasonConnecticut Agricultural Experiment Station, New Haven, Connecticut, USA.ORCID 0000-0002-3866-6399
Elizabeth LinDepartment of Environmental Health, Yale School of Public Health, New Haven, Connecticut, USA.
Brian EitzerConnecticut Agricultural Experiment Station, New Haven, Connecticut, USA.
Jeremy KoelmelDepartment of Environmental Health, Yale School of Public Health, New Haven, Connecticut, USA.
Jordan PecciaDepartment of Chemical and Environmental Engineering, Yale University, New Haven, Connecticut, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The early months of the COVID-19 pandemic and the associated shutdowns disrupted many aspects of daily life and thus caused changes in the use and disposal of many types of chemicals. While records of sales, prescriptions, drug overdoses, and so forth provide data about specific chemical uses during this time, wastewater and sewage sludge analysis can provide a more comprehensive overview of chemical changes within a region. We analyzed primary sludge from a wastewater-treatment plant in Connecticut, USA, collected March 19 to June 30, 2020. This time period encompassed the first wave of the pandemic, the initial statewide stay at home order, and the first phase of reopening. We used liquid chromatography-high-resolution mass spectrometry and targeted and suspect screening strategies to identify 78 chemicals of interest, which included pharmaceuticals, illicit drugs, disinfectants, ultraviolet (UV) filters, and others. We analyzed trends over time for the identified chemicals using linear trend analyses and multivariate comparisons (p < 0.05). We found trends related directly to the pandemic (e.g., hydroxychloroquine, a drug publicized for its potential to treat COVID-19, had elevated concentrations in the week following the implementation of the US Emergency Use Authorization), as well as evidence for seasonal changes in chemical use (e.g., increases for three UV-filter compounds). Though wastewater surveillance during the pandemic has largely focused on measuring severe acute respiratory syndrome-coronavirus-2 RNA concentrations, chemical analysis can also show trends that are important for revealing the public and environmental health effects of the pandemic. Environ Toxicol Chem 2022;41:1179-1192. © 2021 SETAC.

Indexed as

COVID-19DisinfectantsWater Pollutants, ChemicalCommunicable Disease ControlGas Chromatography-Mass SpectrometryHumansMental HealthPandemicsSewageWastewaterWastewater-Based Epidemiological MonitoringDisinfectantsSewageWastewaterWater Pollutants, ChemicalCOVID-19High-resolution mass spectrometryPharmaceuticals and personal care productsSuspect screeningWastewater

Identifiers

PMID34668219
PMCPMC8653241

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.