Evidence map›Paper›PMID 34667840›Full record

ArticleLaryngoscope investigative otolaryngology2021

Quality of life after radiation and transoral robotic surgery in advanced oropharyngeal cancer.

Thomas M Kaffenberger, Ankur K Patel, Lingyun Lyu, Jinhong Li, Tamara Wasserman-Wincko, Dan P Zandberg, David A Clump, Jonas T Johnson, Marci L Nilsen

Open access · goldAbstract read
In one paragraph

Article in Laryngoscope investigative otolaryngology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. A Meta-analysis of Functional Outcomes and Recovery Metrics Comparing Transoral Robotic Surgery and (Chemo)Radiotherapy.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2026
    Pooled it
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  3. Review
  4. Review
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Thomas M KaffenbergerDepartment of Otolaryngology-Head and Neck Surgery University of Pittsburgh School of Medicine Pittsburgh Pennsylvania USA.ORCID https://orcid.org/0000-0002-8411-6806
Ankur K PatelDepartment of Radiation Oncology UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine Pittsburgh Pennsylvania USA.
Lingyun LyuDepartment of Biostatistics University of Pittsburgh School of Public Health Pittsburgh Pennsylvania USA.
Jinhong LiDepartment of Biostatistics University of Pittsburgh School of Public Health Pittsburgh Pennsylvania USA.
Tamara Wasserman-WinckoDepartment of Otolaryngology-Head and Neck Surgery University of Pittsburgh School of Medicine Pittsburgh Pennsylvania USA.
Dan P ZandbergDepartment of Hematology/Oncology UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine Pittsburgh Pennsylvania USA.
David A ClumpDepartment of Radiation Oncology UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine Pittsburgh Pennsylvania USA.
Jonas T JohnsonDepartment of Otolaryngology-Head and Neck Surgery University of Pittsburgh School of Medicine Pittsburgh Pennsylvania USA.ORCID https://orcid.org/0000-0002-2376-4594
Marci L NilsenDepartment of Otolaryngology-Head and Neck Surgery University of Pittsburgh School of Medicine Pittsburgh Pennsylvania USA.ORCID https://orcid.org/0000-0002-5888-668X
University of Pittsburgh · USUPMC Hillman Cancer Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesOropharyngeal squamous cell carcinoma (OPSCC) treatment results in impaired swallowing and quality of life (QOL). We analyzed a cross-section of advanced stage OPSCC patients treated with multimodal therapies at our Survivorship Clinic to investigate treatment factors associated with QOL.

methodsRetrospective analysis of patient-reported outcomes (PROMs) after primary OPSCC treatment using AJCC seventh edition staging.

resultsA total of 73 patients were included (90.1% human papillomavirus positive [HPV+]). There were no QOL differences between robotic surgery with radiation

conclusionsIn advanced, mostly HPV+, OPSCC, we did not find clinically significant differences between QOL PROMs between surgical and radiation LEVEL OF EVIDENCE: 4.

Indexed as

oropharyngeal cancerquality of liferobotic surgerysurvivorshipTORS

Identifiers

PMID34667840
PMCPMC8513430
OpenAlexW3198995124

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.