Evidence map›Paper›PMID 34667699›Full record

ArticlePlastic and reconstructive surgery. Global open2021

Suturable Mesh Demonstrates Improved Outcomes over Standard Suture in a Porcine Laparotomy Closure Model.

Gregory A Dumanian

Abstract read
In one paragraph

Article in Plastic and reconstructive surgery. Global open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Early outcomes of contaminated midline incisional hernia repair with mesh suture.Hernia : the journal of hernias and abdominal wall surgery · 2025
    Article
  4. Mesh suture repair of rectus diastasis with and without a concurrent ventral hernia.Hernia : the journal of hernias and abdominal wall surgery · 2025
    Article
  5. Repair of Massive Pediatric Abdominal Wall Hernia Using Mesh Suture.Plastic and reconstructive surgery. Global open · 2025
    Article
  6. Outcomes Following Implantation With Mesh Suture: A Registry of 1111 Patients.Plastic and reconstructive surgery. Global open · 2025
    Article
  7. Article
  8. Review
  9. Review
  10. Early Experience with Mesh Suture for DIEP Flap Abdominal Site Closures.Plastic and reconstructive surgery. Global open · 2024
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Gregory A DumanianStuteville Professor of Surgery and Chief of Plastic Surgery, Northwestern Feinberg School of Medicine, Chicago, Ill.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLaparotomy closures fail due to suture pull-through. I hypothesize that a suturable mesh may limit pull-through via mechanisms of force distribution and fibrous encapsulation of the device filaments.

methodsFifteen domestic swine 74 kg in size were randomly allocated to three groups for laparotomy closure with either size 0 suturable mesh, number 1 suturable mesh, or number 1 polypropylene. All three devices were placed in running fashion with 1-cm bites and 1-cm travels. Primary endpoints were hernia formation at 13 weeks and a semiquantitative analysis of the histological tissue response. Secondary endpoints included adhesions, surgical site occurrence (SSO), and documentation of "loose sutures."

resultsThere were numerically fewer hernias in the number 1 suturable mesh group. Nine of the 10 suturable mesh devices were well encapsulated within the tissues and could not be pulled away, whereas four of the five polypropylene sutures were loose. Adhesions were least for number 1 suturable mesh. Histologically, the suturable mesh implanted devices showed good fibrovascular ingrowth and were judged to be "nonirritants." The soft-tissue response was statistically greater (

conclusionsThe mechanism by which meshes support closure sites is clearly demonstrated with this model. Suturable mesh has the potential to change surgical algorithms for abdominal wall closure.

Identifiers

PMID34667699
PMCPMC8519206

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.