Evidence map›Paper›PMID 34667571›Full record

ArticleChemical science2021

Trifluoromethyl substitution enhances photoinduced activity against breast cancer cells but reduces ligand exchange in Ru(ii) complex.

Austin P Lanquist, Sayak Gupta, Kathlyn F Al-Afyouni, Malik Al-Afyouni, Jeremy J Kodanko, Claudia Turro

Abstract read
In one paragraph

Article in Chemical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Ruthenium-Based Photoactivated Chemotherapy.Journal of the American Chemical Society · 2023
    Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Austin P LanquistDepartment of Chemistry and Biochemistry, The Ohio State University Columbus OH 43210 USA turro.1@osu.edu.
Sayak GuptaDepartment of Chemistry, Wayne State University Detroit MI 48208 USA jkodanko@chem.wayne.edu.
Kathlyn F Al-AfyouniDepartment of Chemistry and Biochemistry, The Ohio State University Columbus OH 43210 USA turro.1@osu.edu.
Malik Al-AfyouniDepartment of Chemistry and Biochemistry, The Ohio State University Columbus OH 43210 USA turro.1@osu.edu.
Jeremy J KodankoDepartment of Chemistry, Wayne State University Detroit MI 48208 USA jkodanko@chem.wayne.edu.ORCID https://orcid.org/0000-0001-5196-7463
Claudia TurroDepartment of Chemistry and Biochemistry, The Ohio State University Columbus OH 43210 USA turro.1@osu.edu.ORCID https://orcid.org/0000-0003-3202-5870

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A series of five ruthenium complexes containing triphenyl phosphine groups known to enhance both cellular penetration and photoinduced ligand exchange,

Identifiers

PMID34667571
PMCPMC8457392

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.