Evidence map›Paper›PMID 34667546›Full record

ArticleChemical science2021

Excitation ratiometric chloride sensing in a standalone yellow fluorescent protein is powered by the interplay between proton transfer and conformational reorganization.

Cheng Chen, Jasmine N Tutol, Longteng Tang, Liangdong Zhu, Whitney S Y Ong, Sheel C Dodani, Chong Fang

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Cheng ChenDepartment of Chemistry, Oregon State University 153 Gilbert Hall Corvallis OR 97331-4003 USA Chong.Fang@oregonstate.edu https://fanglab.oregonstate.edu/.ORCID https://orcid.org/0000-0003-0561-5226
Jasmine N TutolDepartment of Chemistry and Biochemistry, The University of Texas at Dallas 800 West Campbell Road Richardson TX 75080 USA Sheel.Dodani@utdallas.edu https://lab.utdallas.edu/dodani/.ORCID https://orcid.org/0000-0001-8493-4203
Longteng TangDepartment of Chemistry, Oregon State University 153 Gilbert Hall Corvallis OR 97331-4003 USA Chong.Fang@oregonstate.edu https://fanglab.oregonstate.edu/.ORCID https://orcid.org/0000-0001-9316-188X
Liangdong ZhuDepartment of Chemistry, Oregon State University 153 Gilbert Hall Corvallis OR 97331-4003 USA Chong.Fang@oregonstate.edu https://fanglab.oregonstate.edu/.ORCID https://orcid.org/0000-0003-1747-6585
Whitney S Y OngDepartment of Chemistry and Biochemistry, The University of Texas at Dallas 800 West Campbell Road Richardson TX 75080 USA Sheel.Dodani@utdallas.edu https://lab.utdallas.edu/dodani/.ORCID https://orcid.org/0000-0001-9821-9972
Sheel C DodaniDepartment of Chemistry and Biochemistry, The University of Texas at Dallas 800 West Campbell Road Richardson TX 75080 USA Sheel.Dodani@utdallas.edu https://lab.utdallas.edu/dodani/.ORCID https://orcid.org/0000-0003-0271-6080
Chong FangDepartment of Chemistry, Oregon State University 153 Gilbert Hall Corvallis OR 97331-4003 USA Chong.Fang@oregonstate.edu https://fanglab.oregonstate.edu/.ORCID https://orcid.org/0000-0002-8879-1825
Oregon State University · USThe University of Texas at Dallas · US

Funding

Optical Imaging Tools for Elucidating the Roles of Anions and Anionic Modifications in Cellular SignalingR35GM128923 · NIGMS · UNIVERSITY OF TEXAS DALLAS · PI Sheel Dodani · 2018 to 2026
$3.4M
NIGMS NIH HHS R35 GM128923
6 · The paper itself

Abstract

Natural and laboratory-guided evolution has created a rich diversity of fluorescent protein (FP)-based sensors for chloride (Cl

Identifiers

PMID34667546
PMCPMC8447875
OpenAlexW3190839736

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.