Evidence map›Paper›PMID 34667421›Full record

ArticleAnnals of pediatric cardiology

Tachycardia-induced cardiomyopathy secondary to incessant ectopic atrial tachycardia in two infants: Potential new indication for early initiation of enteral ivabradine.

Balaganesh Karmegaraj, Seshadri Balaji, Prasanna Narayanan Raju, Pradheep Subramanian, Raju Subramanian, Syed Ibrahim, Mohamed Razeen, Raman Krishnakumar

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Annals of pediatric cardiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Tachycardia-Induced Cardiomyopathy: A Case Series and a Literature Review.CJC pediatric and congenital heart disease · 2024
    Review
  5. [Research progress in the application of ivabradine in children with cardiovascular diseases].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2024
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Balaganesh KarmegarajDepartment of Pediatrics, Krishna Maternity Home and Children Hospital, Tirunelveli, Tamil Nadu, India.
Seshadri BalajiDepartment of Pediatrics (Cardiology), Oregon Health and Science University, Portland, Oregon, USA.
Prasanna Narayanan RajuDepartment of Pediatrics, Krishna Maternity Home and Children Hospital, Tirunelveli, Tamil Nadu, India.
Pradheep SubramanianDepartment of Pediatrics, Krishna Maternity Home and Children Hospital, Tirunelveli, Tamil Nadu, India.
Raju SubramanianDepartment of Pediatrics, Krishna Maternity Home and Children Hospital, Tirunelveli, Tamil Nadu, India.
Syed IbrahimDepartment of Pediatrics, Royal hospital, Tirunelveli, India.
Mohamed RazeenDepartment of Pediatrics, Royal hospital, Tirunelveli, India.
Raman KrishnakumarDepartment of Pediatric Cardiology, Amrita Institute of Medical Sciences, Kochi, Kerala, India.
Krishna Maternity and Surgical Nursing Home · INTirunelveli Medical College · INAmrita Institute of Medical Sciences and Research Centre · INOregon Health & Science University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This report describes two cases of tachycardia-induced cardiomyopathy secondary to incessant ectopic atrial tachycardia (EAT) in an infant presenting with severe left ventricular dysfunction and hemodynamic instability. The two cases were managed differently. The first required mechanical ventilation and was resistant to conventional antiarrhythmic drugs. After the initiation of enteral ivabradine (0.15mg/kg) the heart rate slowed with significant improvement in hemodynamics, peripheral perfusion and sinus rhythm was restored after 12 hours. Ivabradine was continued and the patient was discharged home after 10 days of hospitalization. The second case was managed by early initiation of ivabradine and resulted in restoration of sinus rhythm within 4 hours, thus avoiding trials of conventional anti-arrhythmic drugs with unstable hemodynamic profile. The infant was discharged after 5 days of hospitalization on ivabradine..

Indexed as

Ectopic atrial tachycardiainfantivabradinetachycardia-induced cardiomyopathy

Identifiers

PMID34667421
PMCPMC8457284
OpenAlexW3194876141

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.