Evidence map›Paper›PMID 34667396›Full record

ArticleAnnals of pediatric cardiology

Outcome of COVID-19-positive children with heart disease and grown-ups with congenital heart disease: A multicentric study from India.

Sakshi Sachdeva, Sivasubramanian Ramakrishnan, Mrigank Choubey, Nageswara Rao Koneti, Kalaivani Mani, Shweta Bakhru, Saurabh Kumar Gupta, Debasree Gangopadhyay, Soumya Kasturi, Jayashree Mishra and 18 more

Abstract read
In one paragraph

Article in Annals of pediatric cardiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Risk Factors for Pediatric Critical COVID-19: A Systematic Review and Meta-Analysis.Journal of the Pediatric Infectious Diseases Society · 2024
    Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
  7. Risk Factors for Pediatric Critical COVID-19: A Systematic Review and Meta-Analysis.medRxiv : the preprint server for health sciences · 2024
    Article
  8. COVID-19 Vaccines in the Pediatric Population: A Focus on Cardiac Patients.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. COVID-19 in Cyanotic Congenital Heart Disease.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2023
    Review
  13. COVID-19 in congenital heart disease patients: what did we learn?!Frontiers in cardiovascular medicine · 2023
    Article
  14. Article
  15. Pediatric cardiology: Is India self-reliant?Annals of pediatric cardiology
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

Sakshi SachdevaDepartment of Cardiology, All India Institute of Medical Sciences, New Delhi, India.
Sivasubramanian RamakrishnanDepartment of Cardiology, All India Institute of Medical Sciences, New Delhi, India.
Mrigank ChoubeyDepartment of Cardiology, All India Institute of Medical Sciences, New Delhi, India.
Nageswara Rao KonetiDepartment of Pediatric Cardiology, Rainbow Children's Heart Institute, Hyderabad, Telangana, India.
Kalaivani ManiDepartment of Biostatistics, All India Institute of Medical Sciences, New Delhi, India.
Shweta BakhruDepartment of Pediatric Cardiology, Rainbow Children's Heart Institute, Hyderabad, Telangana, India.
Saurabh Kumar GuptaDepartment of Cardiology, All India Institute of Medical Sciences, New Delhi, India.
Debasree GangopadhyayDepartment of Pediatric Cardiology, Narayana Hrudalaya Rabindranath Tagore International Institute of Cardiac Sciences, Kolkata, West Bengal, India.
Soumya KasturiDepartment of Pediatric Cardiology, Sri Jayadeva institute of Cardiovascular Sciences and Research, Bengaluru, Karnataka, India.
Jayashree MishraDepartment of Pediatric Cardiology, Bai Jerbai Wadia Hospital for Children, Mumbai, Maharashtra, India.
Hemant Kumar NayakDepartment of Pediatric Cardiology, Mission Hospital, Durgapur, West Bengal, India.
Kothandam SivakumarDepartment of Pediatric Cardiology, Institute of Cardiovascular Diseases, Madras Medical Mission, Chennai, Tamil Nadu, India.
Prashant BobhateDepartment of Pediatric Cardiology, Kokilaben Dhirubhai Ambani Hospital, Mumbai, Maharashtra, India.
Neeraj AwasthyDepartment of Pediatric Cardiology, Max Super Speciality Hospital, New Delhi, India.
Debasis DasDepartment of Cardiac Surgery, Narayana Superspeciality Hospital, Kolkata, West Bengal, India.
Manisha ChakrabartiDepartment of Pediatric Cardiology, Apollo Hospital, New Delhi, India.
Chinnaswamy Sivaprakasam MuthukumaranDepartment of Pediatric Cardiology, Apollo Hospital, Chennai, Tamil Nadu, India.
Rajan SaileelaDepartment of Pediatric Cardiology, MIOT Centre for Children's Cardiac Care, MIOT Hospital, Chennai, Tamil Nadu, India.
Bhargavi DhulipudiDepartment of Pediatric Cardiology, Rainbow Children's Heart Institute, Hyderabad, Telangana, India.
Shiv Kumar ChaudharyDepartment of Cardio-Thoracic and Vascular Surgery, All India Institute of Medical Sciences, New Delhi, India.
Mahimarangaiah JayranganathDepartment of Pediatric Cardiology, Sri Jayadeva institute of Cardiovascular Sciences and Research, Bengaluru, Karnataka, India.
Anita SaxenaDepartment of Cardiology, All India Institute of Medical Sciences, New Delhi, India.
Krishna Subramony IyerDepartment of Pediatric and Congenital Heart Surgery, Fortis Escorts Heart Institute, New Delhi, India.
Raman Krishna KumarDepartment of Pediatric Cardiology, Amrita Institute of Medical Sciences, Kochi, Kerala, India.
Shyam S KothariDepartment of Cardiology, All India Institute of Medical Sciences, New Delhi, India.
Snehal KulkarniDepartment of Pediatric Cardiology, Kokilaben Dhirubhai Ambani Hospital, Mumbai, Maharashtra, India.
Suresh G RaoChildren's Heart Center, Kokilaben Dhirubhai Ambani Hospital, Mumbai, Maharashtra, India.
PCSI-COVID-19 study group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOutcome data of children with heart disease who acquired COVID-19 infection are limited.

aimsWe sought to analyze outcome data and identify risk factors associated with mortality in children with heart disease and grown-ups with congenital heart disease (GUCH) who had a laboratory-confirmed COVID-19 infection. SETTINGS AND

designThis is a retrospective, multicentric, observational study. MATERIALS AND

methodsThe study included children with heart disease and GUCH population, who presented with either symptomatic or asymptomatic COVID-19 infection to any of the participating centers. COVID-19-negative patients admitted to these centers constituted the control group.

resultsFrom 24 pediatric cardiac centers across India, we included 94 patients with a median age of 12.5 (interquartile range 3-96) months and 49 (52.1%) patients were males. Majority (83 patients, 88.3%) were children. One-third of the patients (

conclusionsChildren with heart disease are at a higher risk of death when they acquire COVID-19 infection. Systematic preventive measures and management strategies are needed for improving the outcomes.

Indexed as

Congenital heart diseasegrown-ups with congenital heart diseaselow- and middle-income countries and SARS-CoV-2 infectionoutcomesurgery

Identifiers

PMID34667396
PMCPMC8457291

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