ReviewThe American journal of case reports2021
A 46-Year-Old Woman with Primary Infertility and a Diagnosis of Microcystic Stromal Tumor of the Ovary Confirmed by Histology and Gene Sequencing: A Case Report and Review of the Literature.
Review in The American journal of case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 4 citations in OpenAlex.
- MRI findings of ovarian microcystic stromal tumor with pathologic correlation: a case report and literature review.Abdominal radiology (New York) · 2026Review
- Testicular microcystic stromal tumor: a case report with MRI findings and literature review.American journal of translational research · 2026Article
- Ovarian microcystic stromal tumor: a case report and literature review.International journal of clinical and experimental pathology · 2025Article
- Ovarian Microcystic Stromal Tumor with Significant Nestin Expression: A Unique Case.Internal medicine (Tokyo, Japan) · 2024Article
- Microcystic stromal tumor of the ovary: a recurrent case with somatic CTNNB1 missense mutation.Virchows Archiv : an international journal of pathology · 2022Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
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Abstract
BACKGROUND Microcystic stromal tumor (MCST) of the ovary is a rare entity with distinct pathological and molecular features. However, a lack of awareness of ovarian MCST can lead to delayed diagnosis or misdiagnosis. We present a case of ovarian MCST and review all previously reported cases and discuss their clinical and pathological characteristics. CASE REPORT A 46-year-old woman with primary infertility due to polycystic ovary syndrome presented with bleeding and pain. Radiological images showed a complex solid and cystic adnexal mass. Microscopically, the tumor was lobulated with cellular regions separated by fibrous plaques and small anastomosing cysts, consistent with an ovarian MCST. The tumor cells showed positive staining for vimentin, CAM 5.2, CD10, ß-Catenin, CD99, and cyclin D1. Genetic sequencing showed a point mutation in the CTNNB1 gene, with no mutations in the APC, BRCA1, and BRCA2 genes. The patient underwent surgery and was disease-free at 24 months after her initial diagnosis. CONCLUSIONS The diagnosis of ovarian MCST should consider the differential diagnosis of cystic tumors of the ovary. Further research is encouraged to elucidate the various molecular pathways involved in the pathogenesis of this tumor and to determine its optimal treatment and long-term prognosis.
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