ArticleJournal of developmental origins of health and disease2022
Maternal childhood trauma and prenatal stressors are associated with child behavioral health.
Article in Journal of developmental origins of health and disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 31 citations in OpenAlex.
- Prenatal psychological distress and neurodevelopmental trajectories in the first 3 years: a systematic review.BMJ open · 2025Pooled it
- The Developmental Origins of Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis.American journal of human biology : the official journal of the Human Biology Council · 2025Pooled it
- A systematic literature review of protective factors mitigating intimate partner violence exposure on early childhood health outcomes.Journal of advanced nursing · 2023Pooled it
- Exploring the Evidence Base on the Association Between Parents' Adverse and Positive Experiences and the Developmental, Psychological and Behavioral Outcomes of Their Offspring: A Scoping Review.Healthcare (Basel, Switzerland) · 2026Review
- Associations between Maternal Adverse Childhood Experiences, Stressful Life Events, and Child Behavioral Outcomes in Racially/Ethnically Diverse Families.Journal of immigrant and minority health · 2026Article
- Early life adversity and adult attention-deficit/hyperactivity disorder (ADHD): Pathways to persistence and adult susceptibility.Neuroscience and biobehavioral reviews · 2025Review
- Converging Evidence of a Specific Vulnerability of Young Boys to Parental Childhood Trauma.JAACAP open · 2025Article
- Associations of maternal neighborhood and trauma-related stressors with mitochondrial DNA copy number and telomere length in maternal and cord blood.Scientific reports · 2025Article
- A longitudinal path model examining the transactional nature of parenting and child externalizing behaviors in a large, sociodemographically diverse sample.Development and psychopathology · 2025Article
- The impact of maternal adverse childhood experiences on children's quality of life: the moderating role of self-esteem and the mediating role of maternal quality of life.Frontiers in global women's health · 2025Article
- Programming the next generation of prenatal programming of stress research: A review and suggestions for the future of the field.Development and psychopathology · 2024Review
- Prenatal exposure to polycyclic aromatic hydrocarbons and executive functions at school age: Results from a combined cohort study.International journal of hygiene and environmental health · 2024Article
- Birth outcomes in relation to neighborhood food access and individual food insecurity during pregnancy in the Environmental Influences on Child Health Outcomes (ECHO)-wide cohort study.The American journal of clinical nutrition · 2024Article
- Sleep and circadian rhythms during pregnancy, social disadvantage, and alterations in brain development in neonates.Developmental science · 2024Article
- The Impact of Maternal Interpersonal Violent Trauma and Related Psychopathology on Child Outcomes and Intergenerational Transmission.Current psychiatry reports · 2024Review
- Examining the impact of prenatal maternal internalizing symptoms and socioeconomic status on children's frontal alpha asymmetry and psychopathology.Developmental psychobiology · 2024Article
- Maternal and Paternal Adverse Childhood Experiences (ACEs) and Offspring Health and Wellbeing: A Scoping Review.Maternal and child health journal · 2024Article
- Intergenerational transmission of stress: Multi-domain stressors from maternal childhood and pregnancy predict children's mental health in a racially and socioeconomically diverse, multi-site cohort.Social psychiatry and psychiatric epidemiology · 2023Article
- Examining Maternal Cardiometabolic Markers in Pregnancy on Child Emotional and Behavior Trajectories: Using Growth Curve Models on a Cohort Study.Biological psychiatry global open science · 2023Article
- A Multi-Cohort Examination of the Independent Contributions of Maternal Childhood Adversity and Pregnancy Stressors to the Prediction of Children's Anxiety and Depression.Research on child and adolescent psychopathology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 4 institutions in 1 country.
Funding
Abstract
Maternal adversity and prenatal stress confer risk for child behavioral health problems. Few studies have examined this intergenerational process across multiple dimensions of stress; fewer have explored potential protective factors. Using a large, diverse sample of mother-child dyads, we examined associations between maternal childhood trauma, prenatal stressors, and offspring socioemotional-behavioral development, while also examining potential resilience-promoting factors. The Conditions Affecting Neurocognitive Development and Learning and Early Childhood (CANDLE) study prospectively followed 1503 mother-child dyads (65% Black, 32% White) from pregnancy. Exposures included maternal childhood trauma, socioeconomic risk, intimate partner violence, and geocode-linked neighborhood violent crime during pregnancy. Child socioemotional-behavioral functioning was measured via the Brief Infant Toddler Social Emotional Assessment (mean age = 1.1 years). Maternal social support and parenting knowledge during pregnancy were tested as potential moderators. Multiple linear regressions (
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.