Evidence map›Paper›PMID 34666793›Full record

ArticleThyroid research2021

Undetectable thyroglobulin makes

Bastiaan Sol, Bert Bravenboer, Brigitte Velkeniers, Steven Raeymaeckers, Marleen Keyaerts, Corina Emilia Andreescu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Thyroid research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.1field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Guideline
  2. The Role ofMedical sciences (Basel, Switzerland) · 2026
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Bastiaan SolDepartment of Endocrinology, UZ Brussel, Laarbeeklaan 101, 1090, Brussels, Belgium. bastiaan.sol1990@gmail.com.ORCID http://orcid.org/0000-0001-6477-1451
Bert BravenboerDepartment of Endocrinology, UZ Brussel, Laarbeeklaan 101, 1090, Brussels, Belgium.
Brigitte VelkeniersDepartment of Endocrinology, UZ Brussel, Laarbeeklaan 101, 1090, Brussels, Belgium.
Steven RaeymaeckersDepartment of Radiology, UZ Brussel, Laarbeeklaan 101, 1090, Brussels, Belgium.
Marleen KeyaertsDepartment of Nuclear Medicine, UZ Brussel, Laarbeeklaan 101, 1090, Brussels, Belgium.
Corina Emilia AndreescuDepartment of Endocrinology, UZ Brussel, Laarbeeklaan 101, 1090, Brussels, Belgium.
Universitair Ziekenhuis Brussel · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDifferentiated thyroid cancer (DTC) is a common malignancy with increasing incidence. Follow-up care for DTC includes thyroglobulin (Tg) measurement and ultrasound (US) of the neck, combined with

methodsThis was a retrospective, observational study. Patients with pathologically confirmed DTC, treated with total thyroidectomy and

resultsForty patients were eligible for analysis. A total of 24 out of the 40 patients (60%) had an undetectable high-sensitive Tg 6 months after total thyroidectomy. None of these patients had a stimulated Tg above 1 ng/mL, or remnant on the

conclusionsThis study shows that an undetectable high-sensitive Tg can change the management of patients with DTC and decrease the use and need of stimulated Tg and

Indexed as

123I whole-body scanDifferentiated thyroid CancerThyroglobulinUltrasound of the neck

Identifiers

PMID34666793
PMCPMC8524885
OpenAlexW3206340427

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.