Evidence map›Paper›PMID 34666693›Full record

ArticleBMC geriatrics2021

The effect of ultraviolet irradiation compared to oral vitamin D supplementation on blood pressure of nursing home residents with dementia.

Bistra I Veleva, Monique A A Caljouw, Astrid Muurman, Jenny T van der Steen, Victor G M Chel, Mattijs E Numans, Rosalinde K E Poortvliet

Open access · goldAbstract read
In one paragraph

Article in BMC geriatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Bistra I VelevaDepartment of Public Health and Primary Care, Leiden University Medical Center, P.O Box 9600, 2300, RC, Leiden, The Netherlands. b.i.todorova-veleva@lumc.nl.
Monique A A CaljouwDepartment of Public Health and Primary Care, Leiden University Medical Center, P.O Box 9600, 2300, RC, Leiden, The Netherlands.
Astrid MuurmanDepartment of Public Health and Primary Care, Leiden University Medical Center, P.O Box 9600, 2300, RC, Leiden, The Netherlands.
Jenny T van der SteenDepartment of Public Health and Primary Care, Leiden University Medical Center, P.O Box 9600, 2300, RC, Leiden, The Netherlands.
Victor G M ChelDepartment of Public Health and Primary Care, Leiden University Medical Center, P.O Box 9600, 2300, RC, Leiden, The Netherlands.
Mattijs E NumansDepartment of Public Health and Primary Care, Leiden University Medical Center, P.O Box 9600, 2300, RC, Leiden, The Netherlands.
Rosalinde K E PoortvlietDepartment of Public Health and Primary Care, Leiden University Medical Center, P.O Box 9600, 2300, RC, Leiden, The Netherlands.
Leiden University Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundObservational studies have reported an inverse association between ultraviolet (UV) radiation and hypertension. The aim of this study was to assess differences in blood pressure changes between persons with dementia receiving UV light versus vitamin D (VD) supplementation.

methodsPost-hoc analysis of randomized controlled trial data concerning nursing home residents with dementia (N = 61; 41 women, mean age 84.8 years). The participants received half-body UV irradiation, twice weekly over 6 months, at one standard erythema dose (UV group, n = 22) or 5600 international units of cholecalciferol once a week (VD group, n = 39). Short-term effects were evaluated after 1 month and long-term effects after 3 and 6 months. Differences in blood pressure changes were assessed using linear mixed models.

resultsWith the VD group as a reference, the estimated difference in mean change of systolic blood pressure was - 26.0 mmHg [95% confidence interval (CI) -39.9, - 12.1, p = .000] at 1 month, 4.5 mmHg (95% CI -6.8, 15.9, p = 0.432) at 3 months, and 0.1 (95% CI -14.1, 14.3, p = 0.83) at 6 months. The estimated difference in diastolic blood pressure was - 10.0 mmHg (95% CI -19.2, - 0.7, p = 0.035) at 1 month, 3.6 mmHg (95% CI -4.1, 11.2, p = 0.358) at 3 months, and 2.7 (95% CI -6.8, 12.1, p = 0.580) at 6 months.

conclusionsUV light had only a short-term effect but not a long-term effect on blood pressure reduction compared to VD use in this sample of normotensive to mild hypertensive nursing home residents with dementia. Future studies will be needed to determine the effect of UV light in different samples of the population and especially in a population with hypertension.

Indexed as

DementiaVitamin DAged, 80 and overBlood PressureDietary SupplementsFemaleHumansNursing HomesUltraviolet RaysVitamin DBlood pressureDementiaNursing homesUVB irradiationVitamin D supplementation

Identifiers

PMID34666693
PMCPMC8524945
OpenAlexW3206548910

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.