Evidence map›Paper›PMID 34666550›Full record

ArticleThe journal of histochemistry and cytochemistry : official journal of the Histochemistry Society2021

Regulation of Endothelial Nitric Oxide Synthase in the Reticular Lamina of the Organ of Corti by a Nitric Oxide Donor.

Ulf-Rüdiger Heinrich, Regina Meuser, Benjamin Philipp Ernst, Irene Schmidtmann, Dimo Dietrich, Roland H Stauber, Sebastian Strieth

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 60% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ulf-Rüdiger HeinrichDepartment of Otorhinolaryngology.
Regina MeuserInstitute for Medical Biometry, Epidemiology and Informatics.
Benjamin Philipp ErnstUniversity Medical Center Mainz, Mainz, Germany, and Department of Otorhinolaryngology, University Medical Center Bonn (UKB), Bonn, Germany.
Irene SchmidtmannInstitute for Medical Biometry, Epidemiology and Informatics.
Dimo DietrichUniversity Medical Center Mainz, Mainz, Germany, and Department of Otorhinolaryngology, University Medical Center Bonn (UKB), Bonn, Germany.
Roland H StauberDepartment of Otorhinolaryngology.
Sebastian StriethUniversity Medical Center Mainz, Mainz, Germany, and Department of Otorhinolaryngology, University Medical Center Bonn (UKB), Bonn, Germany.ORCID 0000-0003-0177-1926
Johannes Gutenberg University Mainz · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the vertebrate cochlea, the reticular lamina seals the organ of Corti against the endolymph filled scala media. After noise exposure, fast alterations in the endothelial nitric oxide synthase (eNOS) expression level were identified in this cochlear structure. Minor amounts of nitric oxide (NO) produced by eNOS or applied by NO donors such as S-nitroso-

Indexed as

AnimalsGuinea PigsMaleNitric Oxide DonorsNitric Oxide Synthase Type IIIOrgan of CortiSpiral LaminaNitric Oxide DonorsNitric Oxide Synthase Type IIIcellular associationscochlear protectioneNOSnitric oxideSNAP

Identifiers

PMID34666550
PMCPMC8554578
OpenAlexW3206906029

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.