Evidence map›Paper›PMID 34665984›Full record

ReviewPediatric hematology and oncology2022

A brief review of the current knowledge on environmental toxicants and risk of pediatric cancers.

Omar Shakeel, Philip J Lupo, Simon Strong, Manish Arora, Michael E Scheurer

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Pediatric hematology and oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Omar ShakeelDepartment of Pediatrics, Baylor College of Medicine, Houston, Texas, USA.ORCID 0000-0002-6583-5012
Philip J LupoDepartment of Pediatrics, Baylor College of Medicine, Houston, Texas, USA.ORCID 0000-0003-0978-5863
Simon StrongThe Oliver Foundation, Miami, Florida, USA.
Manish AroraDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Michael E ScheurerDepartment of Pediatrics, Baylor College of Medicine, Houston, Texas, USA.ORCID 0000-0002-8379-6088
Baylor College of Medicine · USIcahn School of Medicine at Mount Sinai · US

Funding

Translational Research Support CoreP30ES030285 · NIEHS · BAYLOR COLLEGE OF MEDICINE · PI Casey W Wright · 2019 to 2026
$14.7M
NIEHS NIH HHS P30 ES030285
6 · The paper itself

Abstract

The incidence of pediatric cancers has steadily increased since 1975, which could suggest that other exogenous factors are accounting for an increasing proportion of cases. There has been growing concern over environmental exposures (i.e., toxicants) the on development of pediatric cancers. However, identifying environmental exposures on childhood cancer risk has been challenging because these outcomes are infrequent compared to cancer in adults, and it is difficult to estimate exposure during specific critical periods of development (e.g., pre-conception,

Indexed as

Hazardous SubstancesNeoplasmsAdolescentAdultChildChild DevelopmentChild, PreschoolEnvironmental ExposureHumansRisk FactorsHazardous Substancescancer controlenvironmental toxicantsepidemiologyPediatric cancerpediatric oncology

Identifiers

PMID34665984
PMCPMC12707457
OpenAlexW3206563663

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.