Evidence map›Paper›PMID 34665864›Full record

ArticleBlood2022

Aged healthy mice acquire clonal hematopoiesis mutations.

Desmond Wai Loon Chin, Tetsuichi Yoshizato, Stina Virding Culleton, Francesca Grasso, Magdalena Barbachowska, Seishi Ogawa, Sten Eirik W Jacobsen, Petter S Woll

Abstract readLetter
In one paragraph

Article in Blood, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Exacerbation of inflammatory bone loss in TET2-driven clonal hematopoiesis.Journal of immunology (Baltimore, Md. : 1950) · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Clonal dynamics and somatic evolution of haematopoiesis in mouse.bioRxiv : the preprint server for biology · 2024
    Article
  10. The Evolutionary Interplay of Somatic and Germline Mutation Rates.Annual review of biomedical data science · 2024
    Review
  11. Article
  12. Review
  13. Article
  14. Biomarkers of aging.Science China. Life sciences · 2023
    Review
  15. Clonal hematopoiesis and bone marrow inflammation.Translational research : the journal of laboratory and clinical medicine · 2023
    Review
  16. Review
  17. Aging, Causes, and Rejuvenation of Hematopoietic Stem Cells.Advances in experimental medicine and biology · 2023
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Desmond Wai Loon ChinDepartment of Medicine Huddinge, Center for Hematology and Regenerative Medicine, Karolinska Institutet, Stockholm, Sweden.
Tetsuichi YoshizatoDepartment of Medicine Huddinge, Center for Hematology and Regenerative Medicine, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0003-4283-2983
Stina Virding CulletonDepartment of Medicine Huddinge, Center for Hematology and Regenerative Medicine, Karolinska Institutet, Stockholm, Sweden.
Francesca GrassoDepartment of Medicine Huddinge, Center for Hematology and Regenerative Medicine, Karolinska Institutet, Stockholm, Sweden.
Magdalena BarbachowskaDepartment of Medicine Huddinge, Center for Hematology and Regenerative Medicine, Karolinska Institutet, Stockholm, Sweden.
Seishi OgawaDepartment of Medicine Huddinge, Center for Hematology and Regenerative Medicine, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0002-7778-5374
Sten Eirik W JacobsenDepartment of Medicine Huddinge, Center for Hematology and Regenerative Medicine, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0002-1362-3659
Petter S WollDepartment of Medicine Huddinge, Center for Hematology and Regenerative Medicine, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0002-2340-2526

Funding

Medical Research Council G0801073Medical Research Council MC_PC_12020Medical Research Council MC_UU_00016/5Medical Research Council MC_UU_12009/5
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AgingClonal HematopoiesisMutationAgedAnimalsCells, CulturedHematopoietic Stem CellsHumansMice

Identifiers

PMID34665864
PMCPMC8832470

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.