Evidence map›Paper›PMID 34665333›Full record

Article3D printing in medicine2021

Design and 3D-printing of MRI-compatible cradle for imaging mouse tumors.

Deborah L Donohoe, Katherine Dennert, Rajeev Kumar, Bonnie P Freudinger, Alexander J Sherman

Abstract read
In one paragraph

Article in 3D printing in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. An Overview of Anesthetic Procedures for Ferret (Mustela putorius furo) Preclinical Brain MRI: A Call for Standardization.Journal of the American Association for Laboratory Animal Science : JAALAS · 2025
    Review
  3. Article
  4. Article
  5. Comparisons of 3D printed materials for biomedical imaging applications.Science and technology of advanced materials · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Deborah L DonohoeAdvocate Aurora Research Institute, Advocate Aurora Health Care, 960 N. 12th Street, Milwaukee, WI, 53233, USA. deborah.donohoe@aah.org.ORCID http://orcid.org/0000-0002-8808-7133
Katherine DennertAdvocate Aurora Research Institute, Advocate Aurora Health Care, 960 N. 12th Street, Milwaukee, WI, 53233, USA.
Rajeev KumarAdvocate Aurora Research Institute, Advocate Aurora Health Care, 960 N. 12th Street, Milwaukee, WI, 53233, USA.
Bonnie P FreudingerMCW Engineering Core, Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI, 53226, USA.
Alexander J ShermanMCW Engineering Core, Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI, 53226, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe ability of 3D printing using plastics and resins that are magnetic resonance imaging (MRI) compatible provides opportunities to tailor design features to specific imaging needs. In this study an MRI compatible cradle was designed to fit the need for repeatable serial images of mice within a mouse specific low field MRI.

methodsSeveral designs were reviewed which resulted in an open style stereotaxic cradle to fit within specific bore tolerances and allow maximum flexibility with interchangeable radiofrequency (RF) coils. CAD drawings were generated, cradle was printed and tested with phantom material and animals. Images were analyzed for quality and optimized using the new cradle. Testing with multiple phantoms was done to affirm that material choice did not create unwanted image artifact and to optimize imaging parameters. Once phantom testing was satisfied, mouse imaging began.

resultsThe 3D printed cradle fit instrument tolerances, accommodated multiple coil configurations and physiological monitoring equipment, and allowed for improved image quality and reproducibility while also reducing overall imaging time and animal safety.

conclusionsThe generation of a 3D printed stereotaxic cradle was a low-cost option which functioned well for our laboratory.

Indexed as

3D printingLow field MRIMouse imagingMRI cradleStereotaxic device

Identifiers

PMID34665333
PMCPMC8524948

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.