Evidence map›Paper›PMID 34665300›Full record

ArticleKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2022

Strength of interference screw fixation of meniscus prosthesis matches native meniscus attachments.

M K Bartolo, E Provaggi, K K Athwal, S Newman, M A Accardi, D Dini, A Williams, A A Amis

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. The Current State of Meniscus Replacements.Current reviews in musculoskeletal medicine · 2024
    Review
  5. An ovine knee simulator: description and proof of concept.Frontiers in bioengineering and biotechnology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

M K BartoloBiomechanics Group, Mechanical Engineering Department, Imperial College London, London, SW7 2AZ, UK.
E ProvaggiOrthonika Ltd, London, UK.
K K AthwalBiomechanics Group, Mechanical Engineering Department, Imperial College London, London, SW7 2AZ, UK.
S NewmanDepartment of Surgery and Cancer, Imperial College London School of Medicine, London, UK.
M A AccardiOrthonika Ltd, London, UK.
D DiniBiomechanics Group, Mechanical Engineering Department, Imperial College London, London, SW7 2AZ, UK.
A WilliamsBiomechanics Group, Mechanical Engineering Department, Imperial College London, London, SW7 2AZ, UK.
A A AmisBiomechanics Group, Mechanical Engineering Department, Imperial College London, London, SW7 2AZ, UK. a.amis@imperial.ac.uk.ORCID http://orcid.org/0000-0002-4489-1381
Imperial College London · GBUnitika (Japan) · JPFortius Clinic · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeMeniscal surgery is one of the most common orthopaedic surgical interventions. Total meniscus replacements have been proposed as a solution for patients with irreparable meniscal injuries. Reliable fixation is crucial for the success and functionality of such implants. The aim of this study was to characterise an interference screw fixation system developed for a novel fibre-matrix-reinforced synthetic total meniscus replacement in an ovine cadaveric model.

methodsTextile straps were tested in tension to failure (n = 15) and in cyclic tension (70-220 N) for 1000 cycles (n = 5). The textile strap-interference screw fixation system was tested in 4.5 mm-diameter single anterior and double posterior tunnels in North of England Mule ovine tibias aged > 2 years using titanium alloy (Ti6Al4Va) and polyether-ether-ketone (PEEK) screws (n ≥ 5). Straps were preconditioned, dynamically loaded for 1000 cycles in tension (70-220 N), the fixation slippage under cyclic loading was measured, and then pulled to failure.

resultsStrap stiffness was at least 12 times that recorded for human meniscal roots. Strap creep strain at the maximum load (220 N) was 0.005 following 1000 cycles. For all tunnels, pull-out failure resulted from textile strap slippage or bone fracture rather than strap rupture, which demonstrated that the textile strap was comparatively stronger than the interference screw fixation system. Pull-out load (anterior 544 ± 119 N; posterior 889 ± 157 N) was comparable to human meniscal root strength. Fixation slippage was within the acceptable range for anterior cruciate ligament graft reconstruction (anterior 1.9 ± 0.7 mm; posterior 1.9 ± 0.5 mm).

conclusionThese findings show that the textile attachment-interference screw fixation system provides reliable fixation for a novel ovine meniscus implant, supporting progression to in vivo testing. This research provides a baseline for future development of novel human meniscus replacements, in relation to attachment design and fixation methods. The data suggest that surgical techniques familiar from ligament reconstruction may be used for the fixation of clinical meniscal prostheses.

Indexed as

Anterior Cruciate Ligament ReconstructionMeniscusAnimalsAnterior Cruciate LigamentBiomechanical PhenomenaBone ScrewsHumansSheepTibiaCreepFixation systemInterference screwsKneeMeniscusMeniscus replacementOvinePull-out strengthSlippageTensile

Identifiers

PMID34665300
PMCPMC9206603
OpenAlexW3207720885

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.