Evidence map›Paper›PMID 34665281›Full record

GuidelineMedizinische Klinik, Intensivmedizin und Notfallmedizin2021

[Use of extracorporeal circulation (ECLS/ECMO) for cardiac and circulatory failure : Short version of the S3 guideline].

Udo Boeken, Stephan Ensminger, Alexander Assmann, Christof Schmid, Karl Werdan, Guido Michels, Oliver Miera, Florian Schmidt, Stefan Klotz, Christoph Starck and 34 more

Abstract readReviewPractice Guideline
PubMed Publisher
In one paragraph

Guideline in Medizinische Klinik, Intensivmedizin und Notfallmedizin, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. [ECMO therapies in a low-volume, peripheral hospital].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2026
    Article
  2. [Core curriculum of intensive care and emergency medicine in internal medicine].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2025
    Review
  3. Review
  4. Extracorporeal cardiopulmonary resuscitation in 2023.Intensive care medicine experimental · 2023
    Review
  5. Implantation Strategies and ECMO Interhospital Transports.Deutsches Arzteblatt international · 2022
    Article
  6. In Reply.Deutsches Arzteblatt international · 2022
    Article
  7. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

44 authors.

Udo BoekenDepartment of Cardiac Surgery, Heinrich Heine University Medical School, Moorenstraße 5, 40225, Düsseldorf, Deutschland. udo.boeken@med.uni-duesseldorf.de.
Stephan EnsmingerDepartment of Cardiac and Thoracic Vascular Surgery, University Hospital of Schleswig-Holstein, Lübeck, Deutschland.
Alexander AssmannDepartment of Cardiac Surgery, Heinrich Heine University Medical School, Moorenstraße 5, 40225, Düsseldorf, Deutschland.
Christof SchmidDepartment of Cardiothoracic Surgery, University Medical Center Regensburg, Regensburg, Deutschland.
Karl WerdanClinic for Internal Medicine III, University Hospital Halle (Saale), Martin Luther University Halle-Wittenberg, Halle-Wittenberg, Deutschland.
Guido MichelsDepartment of Acute and Emergency Care, St Antonius Hospital Eschweiler, Eschweiler, Deutschland.
Oliver MieraDepartment of Congenital Heart Disease-Pediatric Cardiology, German Heart Center Berlin, Augustenburger Platz 1, 13353, Berlin, Deutschland.
Florian SchmidtDepartment of Pediatric Cardiology and Intensive Care Medicine, Medical School Hannover, Hannover, Deutschland.
Stefan KlotzDepartment of Cardiac Surgery, Segeberger Kliniken, Bad Segeberg, Deutschland.
Christoph StarckDepartment of Cardiothoracic and Vascular Surgery, German Heart Center, Berlin, Deutschland.
Kevin PilarczykImland Hospital Rendsburg, Department for Intensive Care Medicine, Rendsburg, Schleswig-Holstein, Deutschland.
Ardawan RastanDepartment of Cardiac and Vascular Thoracic Surgery, Philipps University Hospital Marburg, Marburg, Deutschland.
Marion BurckhardtDepartment of Health Sciences and Management, Baden-Wuerttemberg Cooperative State University (DHBW)-Stuttgart, Stuttgart, Deutschland.
Monika NothackerInstitute for Medical Knowledge Management, Association of the Scientific Medical Societies (AWMF), Universität Marburg, Marburg, Deutschland.
Ralf MuellenbachDepartment of Anesthesiology and Critical Care Medicine, Campus Kassel of the University of Southampton, Kassel, Deutschland.
York ZausigDepartment of Anesthesiology and Operative Intensive Care Medicine, Aschaffenburg-Alzenau Hospital, Aschaffenburg, Bavaria, Deutschland.
Nils HaakeImland Hospital Rendsburg, Department for Intensive Care Medicine, Rendsburg, Schleswig-Holstein, Deutschland.
Heinrich GroesdonkDepartment of Intensive Care Medicine, Helios Clinic Erfurt, 99089, Erfurt, Deutschland.
Markus FerrariHSK, Clinic of Internal Medicine I, Helios-Kliniken, Wiesbaden, Deutschland.
Michael BuerkeDepartment of Cardiology, Angiology and Internal Intensive Care Medicine, St. Marienkrankenhaus Siegen, Siegen, Deutschland.
Marcus HennersdorfDepartment of Cardiology, Pneumology, Angiology and Internal Intensive Care Medicine, SLK-Kliniken Heilbronn, Heilbronn, Deutschland.
Mark RosenbergDepartment of Internal Medicine I, Hospital Aschaffenburg-Alzenau, Aschaffenburg-Alzenau, Deutschland.
Thomas SchaibleDepartment of Neonatology, University Children's Hospital Mannheim, University of Heidelberg, Mannheim, Deutschland.
Harald KöditzMedical University Children's Hospital, Hannover, Deutschland.
Stefan KlugeDepartment of Intensive Care, University Medical Center Hamburg-Eppendorf, Hamburg, Deutschland.
Uwe JanssensMedical Clinic and Medical Intensive Care Medicine, St Antonius Hospital, Eschweiler, Deutschland.
Matthias LubnowDepartment of Internal Medicine II, University Hospital Regensburg, Regensburg, Deutschland.
Andreas FlemmerDivision of Neonatology, Dr. v. Hauner Children's Hospital and Perinatal Center Munich-Grosshadern, LMU Munich, Munich, Deutschland.
Susanne Herber-JonatDivision of Neonatology, Dr. v. Hauner Children's Hospital and Perinatal Center Munich-Grosshadern, LMU Munich, Munich, Deutschland.
Lucas WesselDepartment of Pediatric Surgery, Medical Faculty Mannheim, University of Heidelberg, Heidelberg, Deutschland.
Dirk BuchwaldDepartment of Cardiothoracic Surgery, University Hospital Bergmannsheil, Ruhr University, Bochum, Deutschland.
Sven MaierDepartment of Cardiovascular Surgery, Heart Center Freiburg University, Freiburg, Deutschland.
Lars KrügerDivision of Thoracic and Cardiovascular Surgery, Heart and Diabetes Center NRW, Ruhr University, Bochum, Deutschland.
Andreas FründDepartment of Physiotherapy, Heart and Diabetes Center NRW, Ruhr University, Bochum, Bochum, Deutschland.
Rolf JakstiesGerman Heart Foundation, Frankfurt am Main, Deutschland.
Stefan FischerDepartment of Thoracic Surgery and Lung Support, Ibbenbueren General Hospital, Ibbenbueren, Deutschland.
Karsten WiebeDepartment of Cardiothoracic Surgery, Münster University Hospital, Münster, Deutschland.
Christiane HartogDepartment of Anesthesiology and Operative Intensive Care Medicine, Charité, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Deutschland.
Omer DzemaliDepartment of Cardiac Surgery, Triemli City Hospital Zurich, Birmensdorferstraße 497, 8063, Zurich, Schweiz.
Daniel ZimpferDepartment of Cardiac Surgery, Medical University of Vienna, Vienna, Österreich.
Elfriede Ruttmann-UlmerDepartment of Cardiac Surgery, Medical University of Innsbruck, Anichstraße 35, 6020, Innsbruck, Österreich.
Christian SchlensakDepartment of Cardiothoracic and Vascular Surgery, University of Tübingen, Tübingen, Deutschland.
Malte KelmDepartment of Cardiology, Pulmonology and Vascular Medicine, Heinrich Heine University Medical School, Moorenstraße 5, Duesseldorf, Deutschland.
Andreas BeckmannGerman Society for Thoracic and Cardiovascular Surgery, Langenbeck-Virchow-Haus, Luisenstraße 58/59, Berlin, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In Germany, a remarkable increase regarding the usage of extracorporeal membrane oxygenation (ECMO) and extracorporeal life support (ECLS) systems has been observed in recent years with approximately 3000 ECLS/ECMO implantations annually since 2015. Despite the widespread use of ECLS/ECMO, evidence-based recommendations or guidelines are still lacking regarding indications, contraindications, limitations and management of ECMO/ECLS patients. Therefore in 2015, the German Society of Thoracic and Cardiovascular Surgery (GSTCVS) registered the multidisciplinary S3 guideline "Use of extracorporeal circulation (ECLS/ECMO) for cardiac and circulatory failure" to develop evidence-based recommendations for ECMO/ECLS systems according to the requirements of the Association of the Scientific Medical Societies in Germany (AWMF). Although the clinical application of ECMO/ECLS represents the main focus, the presented guideline also addresses structural and economic issues. Experts from 17 German, Austrian and Swiss scientific societies and a patients' organization, guided by the GSTCVS, completed the project in February 2021. In this report, we present a summary of the methodological concept and tables displaying the recommendations for each chapter of the guideline.

Indexed as

Extracorporeal Membrane OxygenationShockExtracorporeal CirculationGermanyHumansLife Support SystemsAssociation of the Scientific Medical Societies in GermanyCardiac failureCardiomyopathyECCECLSMechanical circulatory support

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.