Evidence map›Paper›PMID 34665128›Full record

ArticleeLife2021

The inner mechanics of rhodopsin guanylyl cyclase during cGMP-formation revealed by real-time FTIR spectroscopy.

Paul Fischer, Shatanik Mukherjee, Enrico Schiewer, Matthias Broser, Franz Bartl, Peter Hegemann

Open access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Sensing a rainbow of colors: algal photoreceptors.Frontiers in plant science · 2025
    Review
  4. Diversity of rhodopsin cyclases in zoospore-forming fungi.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Paul FischerInstitute for Biology, Experimental Biophysics, Humboldt-Universität zu Berlin, Berlin, Germany.ORCID 0000-0003-3766-9085
Shatanik MukherjeeInstitute of Biology, Biophysical Chemistry, Humboldt University of Berlin, Berlin, Germany.ORCID 0000-0002-7359-9339
Enrico SchiewerInstitute for Biology, Experimental Biophysics, Humboldt-Universität zu Berlin, Berlin, Germany.ORCID 0000-0001-7913-5597
Matthias BroserInstitute for Biology, Experimental Biophysics, Humboldt-Universität zu Berlin, Berlin, Germany.
Franz BartlInstitute of Biology, Biophysical Chemistry, Humboldt University of Berlin, Berlin, Germany.ORCID 0000-0002-0847-867X
Peter HegemannInstitute for Biology, Experimental Biophysics, Humboldt-Universität zu Berlin, Berlin, Germany.ORCID 0000-0003-3589-6452
Humboldt-Universität zu Berlin · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enzymerhodopsins represent a recently discovered class of rhodopsins which includes histidine kinase rhodopsin, rhodopsin phosphodiesterases, and rhodopsin guanylyl cyclases (RGCs). The regulatory influence of the rhodopsin domain on the enzyme activity is only partially understood and holds the key for a deeper understanding of intra-molecular signaling pathways. Here, we present a UV-Vis and FTIR study about the light-induced dynamics of a RGC from the fungus

Indexed as

BlastocladiomycotaCyclic GMPFungal ProteinsGuanylate CyclaseRhodopsinSpectroscopy, Fourier Transform InfraredCyclic GMPFungal ProteinsGuanylate CyclaseRhodopsinbiochemistrycaged compoundcatenaria anguillulaecGMPchemical biologyenzymerhodopsinFTIRmolecular biophysicsoptogeneticrhodopsin guanylyl cyclasestructural biology

Identifiers

PMID34665128
PMCPMC8575461
OpenAlexW3206642329

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.