Evidence map›Paper›PMID 34665054›Full record

ArticleActa radiologica (Stockholm, Sweden : 1987)2022

Peritumoral portal enhancement during transarterial chemoembolization: a potential prognostic factor for patients with hepatocellular carcinoma.

Sofi Sennefelt Nyman, Angeliki Dimopoulou Creusen, Ulf Johnsson, Fredrik Rorsman, Johan Vessby, Charlotte Ebeling Barbier

Abstract read
In one paragraph

Article in Acta radiologica (Stockholm, Sweden : 1987), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sofi Sennefelt NymanDepartment of Surgical Sciences, Section of Radiology, 8097Uppsala University, Uppsala, Sweden.ORCID 0000-0002-8911-2927
Angeliki Dimopoulou CreusenDepartment of Surgical Sciences, Section of Radiology, 8097Uppsala University, Uppsala, Sweden.
Ulf JohnssonDepartment of Surgical Sciences, Section of Radiology, 8097Uppsala University, Uppsala, Sweden.
Fredrik RorsmanDepartment of Medical Sciences, Section of Gastroenterology and Hepatology, 59561Uppsala University, Uppsala, Sweden.
Johan VessbyDepartment of Medical Sciences, Section of Gastroenterology and Hepatology, 59561Uppsala University, Uppsala, Sweden.ORCID 0000-0003-1832-6386
Charlotte Ebeling BarbierDepartment of Surgical Sciences, Section of Radiology, 8097Uppsala University, Uppsala, Sweden.ORCID 0000-0003-4855-5841

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTumor response and survival varies in patients treated with transarterial chemoembolization (TACE) for intermediate stage hepatocellular carcinoma (HCC) and may be associated with several factors. PURPOSE: To evaluate safety and efficacy of TACE in patients with intermediate stage HCC and to identify factors related to tumor response and survival. MATERIAL AND

methodsConsecutive patients with HCC treated with TACE between September 2008 and September 2018 were retrospectively reviewed.

resultsIn 87 patients (71 men; mean age = 68 ± 9 years), 327 TACE treatments were performed (mean = 3/patient; range = 1-12). Mean and median overall survival were 32 and 19 months, respectively. Survival rates at 30 days, one, three, and five years were 99%, 71%, 19%, and 8%, respectively. Objective response (OR) was seen in 84% and disease control (DC) was seen in 92% of the patients. Patients in whom peritumoral portal lipiodol enhancement (PPLE) was seen during TACE had better OR (97 vs. 73%;

conclusionsTACE was effective and safe in patients with intermediate stage HCC. Patients with PPLE during TACE had better tumor response and longer survival than those without PPLE. Severe adverse events occurred more often in patients with larger tumors.

Indexed as

Carcinoma, HepatocellularChemoembolization, TherapeuticLiver NeoplasmsAgedEthiodized OilFemaleHepatocyte Growth FactorHumansMaleMiddle AgedPrognosisRetrospective StudiesTreatment OutcomeEthiodized OilHepatocyte Growth Factorabdomen/GIangiographyHepatocellular carcinomainterventionallivertransarterial chemoembolization

Identifiers

PMID34665054
PMCPMC9490438

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.