Evidence map›Paper›PMID 34665030›Full record

ArticleRadiology2022

Vascular Deformation Mapping for CT Surveillance of Thoracic Aortic Aneurysm Growth.

Nicholas S Burris, Zhangxing Bian, Jeffrey Dominic, Jianyang Zhong, Ignas B Houben, Theodorus M J van Bakel, Himanshu J Patel, Brian D Ross, Gary E Christensen, Charles R Hatt

Abstract read
In one paragraph

Article in Radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  8. Non-Linear Size Effects and Episodic Progression in the Ascending Aorta.medRxiv : the preprint server for health sciences · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Nicholas S BurrisFrom the Departments of Radiology (N.S.B., Z.B., J.D., J.Z., B.D.R., C.R.H.), Biomedical Engineering (N.S.B.), and Electrical Engineering and Computer Science (Z.B., J.D., J.Z.), Center for Molecular Imaging (N.S.B., B.D.R.), and Departments of Cardiac Surgery (I.B.H., T.M.J.v.B., H.J.P.), and Biological Chemistry (B.D.R.), University of Michigan, 1500 E Medical Center Dr, CVC 5588, SPC-5030, Ann Arbor, MI 48109-5030; Department of Electrical and Computer Engineering, University of Iowa, Iowa City, Iowa (G.E.C.); and Imbio, Minneapolis, Minn (C.R.H.).ORCID 0000-0002-5198-4383
Zhangxing BianFrom the Departments of Radiology (N.S.B., Z.B., J.D., J.Z., B.D.R., C.R.H.), Biomedical Engineering (N.S.B.), and Electrical Engineering and Computer Science (Z.B., J.D., J.Z.), Center for Molecular Imaging (N.S.B., B.D.R.), and Departments of Cardiac Surgery (I.B.H., T.M.J.v.B., H.J.P.), and Biological Chemistry (B.D.R.), University of Michigan, 1500 E Medical Center Dr, CVC 5588, SPC-5030, Ann Arbor, MI 48109-5030; Department of Electrical and Computer Engineering, University of Iowa, Iowa City, Iowa (G.E.C.); and Imbio, Minneapolis, Minn (C.R.H.).
Jeffrey DominicFrom the Departments of Radiology (N.S.B., Z.B., J.D., J.Z., B.D.R., C.R.H.), Biomedical Engineering (N.S.B.), and Electrical Engineering and Computer Science (Z.B., J.D., J.Z.), Center for Molecular Imaging (N.S.B., B.D.R.), and Departments of Cardiac Surgery (I.B.H., T.M.J.v.B., H.J.P.), and Biological Chemistry (B.D.R.), University of Michigan, 1500 E Medical Center Dr, CVC 5588, SPC-5030, Ann Arbor, MI 48109-5030; Department of Electrical and Computer Engineering, University of Iowa, Iowa City, Iowa (G.E.C.); and Imbio, Minneapolis, Minn (C.R.H.).ORCID 0000-0002-2363-7528
Jianyang ZhongFrom the Departments of Radiology (N.S.B., Z.B., J.D., J.Z., B.D.R., C.R.H.), Biomedical Engineering (N.S.B.), and Electrical Engineering and Computer Science (Z.B., J.D., J.Z.), Center for Molecular Imaging (N.S.B., B.D.R.), and Departments of Cardiac Surgery (I.B.H., T.M.J.v.B., H.J.P.), and Biological Chemistry (B.D.R.), University of Michigan, 1500 E Medical Center Dr, CVC 5588, SPC-5030, Ann Arbor, MI 48109-5030; Department of Electrical and Computer Engineering, University of Iowa, Iowa City, Iowa (G.E.C.); and Imbio, Minneapolis, Minn (C.R.H.).
Ignas B HoubenFrom the Departments of Radiology (N.S.B., Z.B., J.D., J.Z., B.D.R., C.R.H.), Biomedical Engineering (N.S.B.), and Electrical Engineering and Computer Science (Z.B., J.D., J.Z.), Center for Molecular Imaging (N.S.B., B.D.R.), and Departments of Cardiac Surgery (I.B.H., T.M.J.v.B., H.J.P.), and Biological Chemistry (B.D.R.), University of Michigan, 1500 E Medical Center Dr, CVC 5588, SPC-5030, Ann Arbor, MI 48109-5030; Department of Electrical and Computer Engineering, University of Iowa, Iowa City, Iowa (G.E.C.); and Imbio, Minneapolis, Minn (C.R.H.).ORCID 0000-0001-8975-528X
Theodorus M J van BakelFrom the Departments of Radiology (N.S.B., Z.B., J.D., J.Z., B.D.R., C.R.H.), Biomedical Engineering (N.S.B.), and Electrical Engineering and Computer Science (Z.B., J.D., J.Z.), Center for Molecular Imaging (N.S.B., B.D.R.), and Departments of Cardiac Surgery (I.B.H., T.M.J.v.B., H.J.P.), and Biological Chemistry (B.D.R.), University of Michigan, 1500 E Medical Center Dr, CVC 5588, SPC-5030, Ann Arbor, MI 48109-5030; Department of Electrical and Computer Engineering, University of Iowa, Iowa City, Iowa (G.E.C.); and Imbio, Minneapolis, Minn (C.R.H.).ORCID 0000-0001-5317-3026
Himanshu J PatelFrom the Departments of Radiology (N.S.B., Z.B., J.D., J.Z., B.D.R., C.R.H.), Biomedical Engineering (N.S.B.), and Electrical Engineering and Computer Science (Z.B., J.D., J.Z.), Center for Molecular Imaging (N.S.B., B.D.R.), and Departments of Cardiac Surgery (I.B.H., T.M.J.v.B., H.J.P.), and Biological Chemistry (B.D.R.), University of Michigan, 1500 E Medical Center Dr, CVC 5588, SPC-5030, Ann Arbor, MI 48109-5030; Department of Electrical and Computer Engineering, University of Iowa, Iowa City, Iowa (G.E.C.); and Imbio, Minneapolis, Minn (C.R.H.).
Brian D RossFrom the Departments of Radiology (N.S.B., Z.B., J.D., J.Z., B.D.R., C.R.H.), Biomedical Engineering (N.S.B.), and Electrical Engineering and Computer Science (Z.B., J.D., J.Z.), Center for Molecular Imaging (N.S.B., B.D.R.), and Departments of Cardiac Surgery (I.B.H., T.M.J.v.B., H.J.P.), and Biological Chemistry (B.D.R.), University of Michigan, 1500 E Medical Center Dr, CVC 5588, SPC-5030, Ann Arbor, MI 48109-5030; Department of Electrical and Computer Engineering, University of Iowa, Iowa City, Iowa (G.E.C.); and Imbio, Minneapolis, Minn (C.R.H.).ORCID 0000-0003-2695-9140
Gary E ChristensenFrom the Departments of Radiology (N.S.B., Z.B., J.D., J.Z., B.D.R., C.R.H.), Biomedical Engineering (N.S.B.), and Electrical Engineering and Computer Science (Z.B., J.D., J.Z.), Center for Molecular Imaging (N.S.B., B.D.R.), and Departments of Cardiac Surgery (I.B.H., T.M.J.v.B., H.J.P.), and Biological Chemistry (B.D.R.), University of Michigan, 1500 E Medical Center Dr, CVC 5588, SPC-5030, Ann Arbor, MI 48109-5030; Department of Electrical and Computer Engineering, University of Iowa, Iowa City, Iowa (G.E.C.); and Imbio, Minneapolis, Minn (C.R.H.).ORCID 0000-0002-1473-7375
Charles R HattFrom the Departments of Radiology (N.S.B., Z.B., J.D., J.Z., B.D.R., C.R.H.), Biomedical Engineering (N.S.B.), and Electrical Engineering and Computer Science (Z.B., J.D., J.Z.), Center for Molecular Imaging (N.S.B., B.D.R.), and Departments of Cardiac Surgery (I.B.H., T.M.J.v.B., H.J.P.), and Biological Chemistry (B.D.R.), University of Michigan, 1500 E Medical Center Dr, CVC 5588, SPC-5030, Ann Arbor, MI 48109-5030; Department of Electrical and Computer Engineering, University of Iowa, Iowa City, Iowa (G.E.C.); and Imbio, Minneapolis, Minn (C.R.H.).ORCID 0000-0001-7097-5434

Funding

Imaging of Hematologic and Oncologic DisordersR35CA197701 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ROSS, BRIAN D. · 2016 to 2022
$5.9M
Vascular Deformation Mapping (VDM) for Automated, 3D Assessment of Thoracic Aortic AneurysmR44HL145953 · NHLBI · IMBIO, LLC · PI BURRIS, NICHOLAS SCOTT, HATT, CHARLES R · 2019 to 2022
$1.5M
NCI NIH HHS R35 CA197701NHLBI NIH HHS R44 HL145953
6 · The paper itself

Abstract

Background Aortic diameter measurements in patients with a thoracic aortic aneurysm (TAA) show wide variation. There is no technique to quantify aortic growth in a three-dimensional (3D) manner. Purpose To validate a CT-based technique for quantification of 3D growth based on deformable registration in patients with TAA. Materials and Methods Patients with ascending and descending TAA with two or more CT angiography studies between 2006 and 2020 were retrospectively identified. The 3D aortic growth was quantified using vascular deformation mapping (VDM), a technique that uses deformable registration to warp a mesh constructed from baseline aortic anatomy. Growth assessments between VDM and clinical CT diameter measurements were compared. Aortic growth was quantified as the ratio of change in surface area at each mesh element (area ratio). Manual segmentations were performed by independent raters to assess interrater reproducibility. Registration error was assessed using manually placed landmarks. Agreement between VDM and clinical diameter measurements was assessed using Pearson correlation and Cohen κ coefficients. Results A total of 38 patients (68 surveillance intervals) were evaluated (mean age, 69 years ± 9 [standard deviation]; 21 women), with TAA involving the ascending aorta (

Indexed as

AgedAorta, ThoracicAortic Aneurysm, ThoracicComputed Tomography AngiographyFemaleHumansImaging, Three-DimensionalMaleReproducibility of ResultsRetrospective Studies

Identifiers

PMID34665030
PMCPMC8717815

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.