ArticleBone & joint open2021
Transfusion in orthopaedic surgery : a retrospective multicentre cohort study.
Article in Bone & joint open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.
- Are periprosthetic hip fractures more severe than native hip fractures? A systematic review of outcomes and resource utilization.Archives of orthopaedic and trauma surgery · 2024Pooled it
- The Effect of Intravenous Tranexamic Acid on Perioperative Blood Loss, Transfusion Requirements, Verticalization, and Ambulation in Total Knee Arthroplasty: A Randomized Double-Blind Study.Medicina (Kaunas, Lithuania) · 2024Trial
- Review
- Development of a simple clinical score to estimate in-hospital adverse event risk after elective hip arthroplasty: a retrospective cohort study in a high-risk population.Archives of orthopaedic and trauma surgery · 2025Article
- Reassessing the Necessity of Group and Save Testing in Ambulatory Orthopedic Peripheral Limb Trauma Surgery.Cureus · 2025Article
- orthopedic surgical procedures in patients supported with long-term implantable left ventricular assist devices.Orthopedic reviews · 2025Article
- Postoperative Hemoglobin Drop and the Associated Factors among Elective Orthopedic Surgeries in Northern Tanzania.Advances in orthopedics · 2024Article
- Blood usage among orthopedic patients at the Rivers State University Teaching Hospital, Port Harcourt, Nigeria.Nigerian medical journal : journal of the Nigeria Medical AssociationArticle
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Authors and funding
12 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsOrthopaedic surgeries are complex, frequently performed procedures associated with significant haemorrhage and perioperative blood transfusion. Given refinements in surgical techniques and changes to transfusion practices, we aim to describe contemporary transfusion practices in orthopaedic surgery in order to inform perioperative planning and blood banking requirements.
methodsWe performed a retrospective cohort study of adult patients who underwent orthopaedic surgery at four Canadian hospitals between 2014 and 2016. We studied all patients admitted to hospital for nonarthroscopic joint surgeries, amputations, and fracture surgeries. For each surgery and surgical subgroup, we characterized the proportion of patients who received red blood cell (RBC) transfusion, the mean/median number of RBC units transfused, and exposure to platelets and plasma.
resultsOf the 14,584 included patients, the most commonly performed surgeries were knee arthroplasty (24.8%), hip arthroplasty (24.6%), and hip fracture surgery (17.4%). A total of 10.3% of patients received RBC transfusion; the proportion of patients receiving RBC transfusions varied widely based on the surgical subgroup (0.0% to 33.1%). Primary knee arthroplasty and hip arthroplasty, the two most common surgeries, were associated with in-hospital transfusion frequencies of 2.8% and 4.5%, respectively. RBC transfusion occurred in 25.0% of hip fracture surgeries, accounting for the greatest total number of RBC units transfused in our cohort (38.0% of all transfused RBC units). Platelet and plasma transfusions were uncommon.
conclusionOrthopaedic surgeries were associated with variable rates of transfusion. The rate of RBC transfusion is highly dependent on the surgery type. Identifying surgeries with the highest transfusion rates, and further evaluation of factors that contribute to transfusion in identified at-risk populations, can serve to inform perioperative planning and blood bank requirements, and facilitate pre-emptive transfusion mitigation strategies. Cite this article:
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