Evidence map›Paper›PMID 34664873›Full record

ArticleMedicine2021

Prognostic value of red blood cell distribution width in predicting 3-month functional outcome of patients undergoing thrombolysis treatment for acute ischemic stroke.

Dae Yong Kim, Dae Young Hong, Sin Young Kim, Jeong Jin Park, Jong Won Kim, Sang O Park, Kyeong Ryong Lee, Kwang Je Baek

Open access · goldAbstract read
In one paragraph

Article in Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
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  3. Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Dae Yong KimDepartment of Emergency Medicine, Konkuk University Medical Center, Seoul, Republic of Korea.
Dae Young HongDepartment of Emergency Medicine, Konkuk University School of Medicine, Seoul, Republic of Korea.ORCID 0000-0003-2209-7213
Sin Young KimDepartment of Emergency Medicine, Konkuk University Medical Center, Seoul, Republic of Korea.
Jeong Jin ParkDepartment of Neurology, Konkuk University School of Medicine, Seoul, Republic of Korea.
Jong Won KimDepartment of Emergency Medicine, Konkuk University School of Medicine, Seoul, Republic of Korea.
Sang O ParkDepartment of Emergency Medicine, Konkuk University School of Medicine, Seoul, Republic of Korea.
Kyeong Ryong LeeDepartment of Emergency Medicine, Konkuk University School of Medicine, Seoul, Republic of Korea.
Kwang Je BaekDepartment of Emergency Medicine, Konkuk University School of Medicine, Seoul, Republic of Korea.
Konkuk University · KRKonkuk University Medical Center · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

abstractThis study was performed to determine whether red blood cell distribution width (RDW) is associated with 3-month poor functional outcome in patients undergoing thrombolytic therapy for acute ischemic stroke.RDW was measured in patients with thrombolytic therapy in emergency department. Functional outcome was assessed after 3 months and poor functional outcome was defined as modified Rankin scale 3 to 6.A total of 240 patients were enrolled, and 82 (34.2%) had a poor functional outcome. The median RDW was significantly elevated in patients with a poor functional outcome compare with those with a good outcome. RDW was independently associated with a 3-month poor functional outcome (odds ratio 3.369, 95% confidence interval 2.214-5.125). The optimal RDW cutoff for predicting 3-month poor functional outcome was 12.8%, and the area under the curve for RDW was 0.818 (95% confidence interval 0.761-0.876). The area under the curve for RDW was higher in male patients than in female patients. The RDW correlated positively with the modified Rankin scale score after 3 months and the initial National Institutes of Health Stroke Scale score.Initial higher RDW level is related to a 3-month poor functional outcome in patients undergoing thrombolytic therapy for acute ischemic stroke.

Indexed as

AgedAged, 80 and overArea Under CurveErythrocytesFemaleHumansIschemic StrokeLogistic ModelsMaleMiddle AgedOdds RatioOutcome Assessment, Health CarePrognosisRetrospective StudiesROC CurveSeoul

Identifiers

PMID34664873
PMCPMC8447982
OpenAlexW3200005734

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.