Evidence map›Paper›PMID 34664798›Full record

ArticleJournal of Korean medical science2021

Evaluation of Adherence to Guideline for Heart Failure with Reduced Ejection Fraction in Heart Failure with Preserved Ejection Fraction and with or without Atrial Fibrillation.

Min-Soo Ahn, Byung-Su Yoo, Jung-Woo Son, Young Jun Park, Hae-Young Lee, Eun-Seok Jeon, Seok-Min Kang, Dong-Ju Choi, Kye Hun Kim, Myeong-Chan Cho and 3 more

Abstract read
In one paragraph

Article in Journal of Korean medical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Min-Soo AhnDepartment of Internal Medicine, Wonju College of Medicine, Yonsei University, Wonju, Korea.ORCID https://orcid.org/0000-0001-7896-8175
Byung-Su YooDepartment of Internal Medicine, Wonju College of Medicine, Yonsei University, Wonju, Korea. yubs@yonsei.ac.kr.ORCID https://orcid.org/0000-0002-3395-4279
Jung-Woo SonDepartment of Internal Medicine, Wonju College of Medicine, Yonsei University, Wonju, Korea.ORCID https://orcid.org/0000-0002-1790-3228
Young Jun ParkDepartment of Internal Medicine, Wonju College of Medicine, Yonsei University, Wonju, Korea.ORCID https://orcid.org/0000-0002-1461-5597
Hae-Young LeeDepartment of Internal Medicine, Seoul National University Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0002-9521-4102
Eun-Seok JeonDepartment of Internal Medicine, Sungkyunkwan University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-9946-5611
Seok-Min KangDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-9856-9227
Dong-Ju ChoiDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.ORCID https://orcid.org/0000-0003-0146-2189
Kye Hun KimDepartment of Internal Medicine, Heart Research Center of Chonnam National University, Gwangju, Korea.ORCID https://orcid.org/0000-0002-6885-1501
Myeong-Chan ChoDepartment of Internal Medicine, Chungbuk National University College of Medicine, Cheongju, Korea.ORCID https://orcid.org/0000-0002-0047-0227
Seong Yoon KimMetroWest Medical Center, Framingham, MA, USA.ORCID https://orcid.org/0000-0003-0490-0447
Dae Ryong KangDepartment of Biostatics, Wonju College of Medicine, Yonsei University, Wonju, Korea.ORCID https://orcid.org/0000-0002-8792-9730
Tae-Hwa GoDepartment of Biostatics, Wonju College of Medicine, Yonsei University, Wonju, Korea.ORCID https://orcid.org/0000-0003-4386-0134

Funding

Korea Centers for Disease Control and Prevention 2010-E63003-00Korea Centers for Disease Control and Prevention 2011-E63002-00Korea Centers for Disease Control and Prevention 2012-E63005-00Korea Centers for Disease Control and Prevention 2013-E63003-00Korea Centers for Disease Control and Prevention 2013-E63003-01Korea Centers for Disease Control and Prevention 2013-E63003-02Korea Centers for Disease Control and Prevention 2016-ER6303-00Korea Centers for Disease Control and Prevention 2019ER630300
6 · The paper itself

Abstract

backgroundThis study evaluated the relationship between guideline adherence for heart failure (HF) with reduced ejection fraction (HFrEF) at discharge and relevant clinical outcomes in patients with acute HF with preserved ejection fraction (HFpEF) with or without atrial fibrillation (AF).

methodsWe analyzed Korean Acute Heart Failure Registry data for 707 patients with HFpEF with documented AF and 687 without AF. Guideline adherence was defined as good or poor according to the prescription of angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, β-blockers, and mineralocorticoid receptor antagonists. Anticoagulation adherence was also incorporated for the AF group.

resultsAmong patients with normal sinus rhythm, those with poor guideline adherence had a reduced prevalence of comorbidities and favorable clinical characteristics when compared with those with good guideline adherence. Using inverse probability of treatment weighting (IPTW) to address the bias of nonrandom treatment assignment, good adherence was associated with a poor 60-day composite endpoint in the multivariable Cox model (weighted hazard ratio [wHR], 1.74; 95% confidence interval [CI], 1.01-3.00;

conclusionOur findings indicate that good adherence to guidelines for HFrEF is associated with a better 60-day composite endpoint in patients with HFpEF with AF.

Indexed as

Medication AdherenceAdrenergic beta-AntagonistsAgedAged, 80 and overAngiotensin-Converting Enzyme InhibitorsAngiotensin Receptor AntagonistsAtrial FibrillationFemaleHeart FailureHumansMaleMiddle AgedPatient DischargePatient ReadmissionProportional Hazards ModelsRegistriesAdrenergic beta-AntagonistsAngiotensin-Converting Enzyme InhibitorsAngiotensin Receptor AntagonistsAtrial FibrillationGuideline AdherenceHeart Failure

Identifiers

PMID34664798
PMCPMC8524233

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.