Evidence map›Paper›PMID 34664543›Full record

ArticleExpert review of vaccines2021

Vaccines against leishmaniasis: using controlled human infection models to accelerate development.

Vivak Parkash, Paul M Kaye, Alison M Layton, Charles J Lacey

Abstract read
In one paragraph

Article in Expert review of vaccines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Observational
  5. Review
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Vivak ParkashYork Biomedical Research Institute, Hull York Medical School, University of York, York, UK.
Paul M KayeYork Biomedical Research Institute, Hull York Medical School, University of York, York, UK.
Alison M LaytonYork Biomedical Research Institute, Hull York Medical School, University of York, York, UK.
Charles J LaceyYork Biomedical Research Institute, Hull York Medical School, University of York, York, UK.

Funding

Medical Research Council MR/R014973/1Wellcome Trust
6 · The paper itself

Abstract

introductionLeishmaniasis is a neglected tropical disease that is defined by the World Health Organization as vaccine preventable. Although several new candidate vaccines are in development, no vaccine has successfully reached the market for human use. Several species of AREAS COVERED: We describe the history and recent development of experimental and deliberate infection using EXPERT OPINION: A new cutaneous

Indexed as

LeishmaniaLeishmaniasisLeishmaniasis VaccinesLeishmaniasis, VisceralPsychodidaeAnimalsHumansSkinLeishmaniasis VaccinesControlled human infection model (CHIM)experimental infectionexperimental modelshuman challengeleishmaniasisvaccines

Identifiers

PMID34664543
PMCPMC9835556

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.