Evidence map›Paper›PMID 34664422›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2021

A Sequential Dual-Model Strategy Based on Photoactivatable Metallopolymer for On-Demand Release of Photosensitizers and Anticancer Drugs.

Maomao He, Guangli He, Peiyuan Wang, Suhua Jiang, Ziyue Jiao, Dongmei Xi, Pengcheng Miao, Xuefei Leng, Zhiyong Wei, Yang Li and 6 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 41 citations in OpenAlex.

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  5. Chemical Reactions in Living Systems.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 1 country.

Maomao HeState Key Laboratory of Fine Chemicals, Liaoning key Laboratory of Polymer Science and Engineering, School of Chemical Engineering, Dalian University of Technology, Dalian, 116024, China.
Guangli HeState Key Laboratory of Fine Chemicals, Liaoning key Laboratory of Polymer Science and Engineering, School of Chemical Engineering, Dalian University of Technology, Dalian, 116024, China.
Peiyuan WangCAS Key Laboratory of Design and Assembly of Functional Nanostructures, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, 350002, China.
Suhua JiangCAS Key Laboratory of Design and Assembly of Functional Nanostructures, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, 350002, China.
Ziyue JiaoState Key Laboratory of Fine Chemicals, Liaoning key Laboratory of Polymer Science and Engineering, School of Chemical Engineering, Dalian University of Technology, Dalian, 116024, China.
Dongmei XiState Key Laboratory of Fine Chemicals, Liaoning key Laboratory of Polymer Science and Engineering, School of Chemical Engineering, Dalian University of Technology, Dalian, 116024, China.
Pengcheng MiaoState Key Laboratory of Fine Chemicals, Liaoning key Laboratory of Polymer Science and Engineering, School of Chemical Engineering, Dalian University of Technology, Dalian, 116024, China.
Xuefei LengState Key Laboratory of Fine Chemicals, Liaoning key Laboratory of Polymer Science and Engineering, School of Chemical Engineering, Dalian University of Technology, Dalian, 116024, China.
Zhiyong WeiState Key Laboratory of Fine Chemicals, Liaoning key Laboratory of Polymer Science and Engineering, School of Chemical Engineering, Dalian University of Technology, Dalian, 116024, China.
Yang LiState Key Laboratory of Fine Chemicals, Liaoning key Laboratory of Polymer Science and Engineering, School of Chemical Engineering, Dalian University of Technology, Dalian, 116024, China.
Yanjun YangState Key Laboratory of Fine Chemicals, Liaoning key Laboratory of Polymer Science and Engineering, School of Chemical Engineering, Dalian University of Technology, Dalian, 116024, China.
Ran WangState Key Laboratory of Fine Chemicals, Liaoning key Laboratory of Polymer Science and Engineering, School of Chemical Engineering, Dalian University of Technology, Dalian, 116024, China.
Jianjun DuState Key Laboratory of Fine Chemicals, Liaoning key Laboratory of Polymer Science and Engineering, School of Chemical Engineering, Dalian University of Technology, Dalian, 116024, China.
Jiangli FanState Key Laboratory of Fine Chemicals, Liaoning key Laboratory of Polymer Science and Engineering, School of Chemical Engineering, Dalian University of Technology, Dalian, 116024, China.
Wen SunState Key Laboratory of Fine Chemicals, Liaoning key Laboratory of Polymer Science and Engineering, School of Chemical Engineering, Dalian University of Technology, Dalian, 116024, China.ORCID 0000-0003-4316-5350
Xiaojun PengState Key Laboratory of Fine Chemicals, Liaoning key Laboratory of Polymer Science and Engineering, School of Chemical Engineering, Dalian University of Technology, Dalian, 116024, China.
Dalian University of Technology · CNChinese Academy of Sciences · CN

Funding

National Key R&D Program of China 2017YFB0307100National Key R&D Program of China 2017YFB0307101National Science Foundation of China 21808028National Science Foundation of China 22022803National Science Foundation of China 22078046Science and Technology Foundation of Liaoning Province 2019-BS-047
6 · The paper itself

Abstract

The synergistic combination of chemotherapy and photodynamic therapy has attracted considerable attention for its enhanced antitumoral effects; however, it remains challenging to successfully delivery photosensitizers and anticancer drugs while minimizing drug leakage at off-target sites. A red-light-activatable metallopolymer, Poly(Ru/PTX), is synthesized for combined chemo-photodynamic therapy. The polymer has a biodegradable backbone that contains a photosensitizer Ru complex and the anticancer drug paclitaxel (PTX) via a singlet oxygen (

Indexed as

chemo-photodynamic therapymetallopolymeron-demand drug releaseROS-responsiveRu complexes

Identifiers

PMID34664422
PMCPMC8655221
OpenAlexW3206384984

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.