Evidence map›Paper›PMID 34664184›Full record

ArticleJournal of assisted reproduction and genetics2021

A novel posttranslational modification of histone, H3 S-sulfhydration, is down-regulated in asthenozoospermic sperm.

Qi Qi, Hongjie Pan, Ning Jiang, Meixin Zhang, Shenfei Sun, Xiaofeng Wan, Fangxi Zhang, Lingling Zhang, Hua Diao, Jian Wang and 1 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of assisted reproduction and genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Qi QiNHC Key Laboratory of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research), Pharmacy School, Fudan University, 2140 Xietu Road, Shanghai, 200032, China.
Hongjie PanNHC Key Laboratory of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research), Pharmacy School, Fudan University, 2140 Xietu Road, Shanghai, 200032, China.
Ning JiangState Key Laboratory of Genetic Engineering, Institute of Biostatistics and Computational Biology, School of Life Sciences, Fudan University, Shanghai, 200438, China.
Meixin ZhangNHC Key Laboratory of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research), 2140 Xietu Road, Shanghai, 200032, China.
Shenfei SunNHC Key Laboratory of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research), School of Life Sciences, Fudan University, 2140 Xietu Road, Shanghai, 200032, China.
Xiaofeng WanNHC Key Laboratory of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research), 2140 Xietu Road, Shanghai, 200032, China.
Fangxi ZhangNHC Key Laboratory of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research), Pharmacy School, Fudan University, 2140 Xietu Road, Shanghai, 200032, China.
Lingling ZhangNHC Key Laboratory of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research), Pharmacy School, Fudan University, 2140 Xietu Road, Shanghai, 200032, China.
Hua DiaoNHC Key Laboratory of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research), 2140 Xietu Road, Shanghai, 200032, China.
Jian WangNHC Key Laboratory of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research), 2140 Xietu Road, Shanghai, 200032, China.
Runsheng LiNHC Key Laboratory of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research), Pharmacy School, Fudan University, 2140 Xietu Road, Shanghai, 200032, China. runshengli2007@163.com.ORCID http://orcid.org/0000-0001-7943-0625
Fudan University · CNShanghai Institute of Planned Parenthood Research · CN

Funding

national natural science foundation of china 81571495natural science foundation of tianjin municipal science and technology commission 81971443shanghai municipal commission of economy and informatization 21140903600shanghai municipal health and health commission clinical research project 20194Y0237Shanghai Municipal Science and Technology Commission 21S11901000
6 · The paper itself

Abstract

Oxidative stress is one of the major causes leading to male infertility including asthenozoospermia. Hydrogen sulfide (H

Indexed as

Amino Acid SequenceAnimalsAsthenozoospermiaBiotinCysteineGene Expression RegulationHistonesHumansHydrogen SulfideInfertilityMaleMiceMice, Inbred C57BLMutationProtein Processing, Post-TranslationalSpermatogenesisBiotinCysteineHistonesHydrogen SulfideSulfhydryl CompoundsSulfidesAsthenozoospermiaH3.3H3S-sulfhydrationSpermatogenesisS-sulfhydrated proteome

Identifiers

PMID34664184
PMCPMC8666411
OpenAlexW3205769473

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.