Evidence map›Paper›PMID 34664138›Full record

ArticlePflugers Archiv : European journal of physiology2021

Beyond Ca

Hendrik Liebe, Franziska Liebe, Gerhard Sponder, Sarah Hedtrich, Friederike Stumpff

Open access · hybridAbstract read
In one paragraph

Article in Pflugers Archiv : European journal of physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. TRPV3 Ion Channel: From Gene to Pharmacology.International journal of molecular sciences · 2023
    Review
  6. Review
  7. Article
  8. Effects of butyratePflugers Archiv : European journal of physiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Hendrik LiebeInstitute of Veterinary Physiology, Freie Universität Berlin, Oertzenweg 19b, 14163, Berlin, Germany.ORCID http://orcid.org/0000-0002-2545-9358
Franziska LiebeInstitute of Veterinary Physiology, Freie Universität Berlin, Oertzenweg 19b, 14163, Berlin, Germany.ORCID http://orcid.org/0000-0002-4722-3709
Gerhard SponderInstitute of Veterinary Physiology, Freie Universität Berlin, Oertzenweg 19b, 14163, Berlin, Germany.ORCID http://orcid.org/0000-0002-5588-1250
Sarah HedtrichFaculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, Canada.ORCID http://orcid.org/0000-0001-6770-3657
Friederike StumpffInstitute of Veterinary Physiology, Freie Universität Berlin, Oertzenweg 19b, 14163, Berlin, Germany. stumpff@zedat.fu-berlin.de.ORCID http://orcid.org/0000-0001-9518-9237
Freie Universität Berlin · DEUniversity of British Columbia · CA

Funding

Deutsche Forschungsgemeinschaft STU 258/7-1
6 · The paper itself

Abstract

Mutations of TRPV3 lead to severe dermal hyperkeratosis in Olmsted syndrome, but whether the mutants are trafficked to the cell membrane or not is controversial. Even less is known about TRPV3 function in intestinal epithelia, although research on ruminants and pigs suggests an involvement in the uptake of NH

Indexed as

AmmoniaAnimalsBiological TransportCalcium SignalingCell LineCell MembraneCell Membrane PermeabilityEpitheliumHEK293 CellsHumansHydrogen-Ion ConcentrationKeratinocytesMutationOocytesPatch-Clamp TechniquesTRPV Cation ChannelsAmmoniaTRPV3 protein, humanTRPV Cation ChannelsAmmoniaColonNH4 +Olmsted syndromeSkinTRPV3

Identifiers

PMID34664138
PMCPMC8599221
OpenAlexW3207867495

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.