Evidence map›Paper›PMID 34664126›Full record

ArticleChild psychiatry and human development2023

Neurophysiological Correlates of Sensory-Based Phenotypes in ASD.

Kelle K DeBoth, Stacey Reynolds, Shelly J Lane, Henry Carretta, Alison E Lane, Roseann C Schaaf

Abstract read
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In one paragraph

Article in Child psychiatry and human development, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 2 countries.

Kelle K DeBothDepartment of Occupational Therapy, Cleveland State University, 2121 Euclid Ave. IM 323, Cleveland, OH, 44115, USA. k.deboth@csuohio.edu.ORCID 0000-0002-6349-2458
Stacey ReynoldsDepartment of Occupational Therapy, Virginia Commonwealth University, Richmond, VA, USA.
Shelly J LaneDepartment of Occupational Therapy, Colorado State University, Fort Collins, CO, USA.
Henry CarrettaCollege of Medicine, Florida State University, Tallahassee, FL, USA.
Alison E LaneDepartment of Occupational Therapy, University of Newcastle, Newcastle, Australia.
Roseann C SchaafDepartment of Occupational Therapy, Thomas Jefferson University, Philadelphia, PA, USA.
Cleveland State University · USColorado State University · USFlorida State University · USThomas Jefferson University · USUniversity of Newcastle Australia · AUVirginia Commonwealth University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Children with autism spectrum disorder frequently present with atypical behavioral responses to sensory stimuli, as well as differences in autonomic nervous system (ANS) and neuroendocrine activity. However, no one consistent pattern appears to explain these differences within this heterogeneous population. To conceptualize more homogenous ASD subgroups, sensory-based subtypes have been explored. One subtyping mechanism groups children by sensory responsivity pattern in addition to sensory domain. Differences in nervous system responsivity to sensory input within this sensory-based subtyping scheme have not yet been investigated. This exploratory study used ANS indices (respiratory sinus arrhythmia [RSA], skin conductance level) and neuroendocrine (salivary cortisol) response to examine patterns differentiating these subtypes. Significant differences in RSA were found during baseline, and during tactile, tone and movement stimuli (p < 0.05). Subtype membership was predicted by RSA changes during auditory stimulation and recovery periods (p < 0.05). Results confirm that children with an adaptive sensory responsivity subtype differ from those children with sensory processing dysfunction, however, physiological variables did not distinguish between children with different patterns of sensory processing dysfunction.

Indexed as

Autism Spectrum DisorderRespiratory Sinus ArrhythmiaAutonomic Nervous SystemHumansPhenotypeAutism spectrum disorderAutonomic nervous systemElectrodermal activityHeart rate variabilitySubtypes

Identifiers

PMID34664126
OpenAlexW3206379296

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.