ArticleNature metabolism2021
5-IP
Abstract read
In one paragraph
Article in Nature metabolism, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 35 citations in OpenAlex.
- Structural insights into the development of inhibitors for inositol phosphate kinases.FEBS letters · 2026Review
- Inositol pyrophosphate kinases in health and disease.FEBS letters · 2026Review
- Analytical methods and tools for studying inositol phosphates.FEBS letters · 2026Review
- Targeting the Ip6k2-Runx2 axis disrupts osteoblast-osteoclast coupling to treat osteoporosis.Nature communications · 2026Article
- Proteome-wide quantification of inositol pyrophosphate-protein interactions.Nature communications · 2026Article
- Oncometabolite 5-IPNature chemical biology · 2026Article
- GA-independent DELLA regulation by inositol pyrophosphate in a nonvascular land plant.Nature chemical biology · 2025Article
- Adipose Inositol Monophosphate Metabolism Is Associated with Fasting Regimen-Elicited Metabolic Benefits.Biomolecules · 2025Article
- Physiological roles of phosphoinositides and inositol phosphates: Implications for metabolic dysfunction-associated steatotic liver disease.Clinical science (London, England : 1979) · 2025Review
- Conservation of heat stress acclimation by the IPK2-type kinases that control the synthesis of the inositol pyrophosphate 4/6-InsP7 in land plants.PLoS genetics · 2025Article
- March5-mediated Trim28 degradation preserves islet β-cell function in mice.Nature communications · 2025Article
- SYT7 accelerates nasopharyngeal carcinoma progression via ALDH1A3-mediated STAT3 signaling activation.Oncogenesis · 2025Article
- Metabolic-stress-induced mitochondrial calcium dysregulation: a central hub in diabetic cardiomyopathy pathogenesis and treatment.Frontiers in endocrinology · 2025Review
- Knockout Mice as an Experimental Model to Study the Biology of Inositol Pyrophosphates.Methods in molecular biology (Clifton, N.J.) · 2025Article
- Insights into the roles of inositol hexakisphosphate kinase 1 (IP6K1) in mammalian cellular processes.The Journal of biological chemistry · 2024Review
- Functions, Mechanisms, and therapeutic applications of the inositol pyrophosphates 5PP-InsPJournal of cardiovascular translational research · 2024Review
- Expedient synthesis and luminescence sensing of the inositol pyrophosphate cellular messenger 5-PP-InsPChemical science · 2023Article
- Proteomics Analysis of R-Ras Deficiency in Oxygen Induced Retinopathy.International journal of molecular sciences · 2023Article
- One Scaffold, Two Conformations: The Ring-Flip of the Messenger InsPBiomolecules · 2023Article
- Nucleolar Architecture Is Modulated by a Small Molecule, the Inositol Pyrophosphate 5-InsPBiomolecules · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
33 authors at 7 institutions in 2 countries.
Xiaozhe Zhang *School of Life Sciences, Southern University of Science and Technology, Shenzhen, China.
Na Li *School of Life Sciences, Southern University of Science and Technology, Shenzhen, China.
Jun Zhang *School of Life Sciences, Southern University of Science and Technology, Shenzhen, China.ORCID http://orcid.org/0000-0001-5521-2092
Yanshen Zhang *Ministry of Education Key Laboratory for Membraneless Organelles & Cellular Dynamics, Hefei National Laboratory for Physical Sciences at the Microscale, School of Life Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Xiaoli Yang *School of Life Sciences, Southern University of Science and Technology, Shenzhen, China.
Yifan LuoSchool of Life Sciences, Southern University of Science and Technology, Shenzhen, China.
Bobo ZhangSchool of Life Sciences, Southern University of Science and Technology, Shenzhen, China.
Zhixue XuSchool of Life Sciences, Southern University of Science and Technology, Shenzhen, China.
Zhenhua ZhuSchool of Life Sciences, Southern University of Science and Technology, Shenzhen, China.
Xiuyan YangSchool of Life Sciences, Southern University of Science and Technology, Shenzhen, China.
Yuan YanSchool of Life Sciences, Southern University of Science and Technology, Shenzhen, China.
Biao LinSchool of Life Sciences, Southern University of Science and Technology, Shenzhen, China.
Shen WangKey Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.ORCID http://orcid.org/0000-0002-5013-1039
Da ChenMinistry of Education Key Laboratory for Membraneless Organelles & Cellular Dynamics, Hefei National Laboratory for Physical Sciences at the Microscale, School of Life Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Caichao YeDepartment of Physics and Shenzhen Institute for Quantum Science & Technology, Southern University of Science and Technology, Shenzhen, China.ORCID http://orcid.org/0000-0002-9197-8922
Yan DingNational Institute of Biological Sciences, Beijing, China.
Mingliang LouNational Institute of Biological Sciences, Beijing, China.
Qingcui WuNational Institute of Biological Sciences, Beijing, China.
Zhanfeng HouNational Institute of Biological Sciences, Beijing, China.
Keren ZhangBGI-Shenzhen, Beishan Industrial Zone 11th building, Shenzhen, China.
Ziming LiangDepartment of Hepatic Surgery, the Third People's Hospital of Shenzhen and the Second Affiliated Hospital of Southern University of Science and Technology, Shenzhen, China.
Anqi WeiNeuroscience Research Center, Institute of Mitochondrial Biology and Medicine, Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, China.
Bianbian WangNeuroscience Research Center, Institute of Mitochondrial Biology and Medicine, Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, China.
Changhe WangNeuroscience Research Center, Institute of Mitochondrial Biology and Medicine, Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, China.
Nan JiangDepartment of Hepatic Surgery, the Third People's Hospital of Shenzhen and the Second Affiliated Hospital of Southern University of Science and Technology, Shenzhen, China.
Wenqing ZhangDepartment of Physics and Shenzhen Institute for Quantum Science & Technology, Southern University of Science and Technology, Shenzhen, China.
Guozhi XiaoDepartment of Biochemistry, School of Medicine, Southern University of Science and Technology, Guangdong Provincial Key Laboratory of Cell Microenvironment and Disease Research, Shenzhen Key Laboratory of Cell Microenvironment, Shenzhen, China.
Cong MaKey Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.
Yan RenBGI-Shenzhen, Beishan Industrial Zone 11th building, Shenzhen, China.
Xiangbing QiNational Institute of Biological Sciences, Beijing, China.ORCID http://orcid.org/0000-0002-7139-5164
Weiping HanInstitute of Molecular and Cell Biology, Agency for Science, Technology, and Research, Singapore, Singapore.
Chao WangMinistry of Education Key Laboratory for Membraneless Organelles & Cellular Dynamics, Hefei National Laboratory for Physical Sciences at the Microscale, School of Life Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China. cwangust@ustc.edu.cn.ORCID http://orcid.org/0000-0003-3192-2780
Feng RaoSchool of Life Sciences, Southern University of Science and Technology, Shenzhen, China. raof@sustech.edu.cn.ORCID http://orcid.org/0000-0002-6038-6406
Southern University of Science and Technology · CNNational Institute of Biological Sciences, Beijing · CNUniversity of Science and Technology of China · CNBGI Group (China) · CNHuazhong University of Science and Technology · CNXi'an Jiaotong University · CNAgency for Science, Technology and Research · SG
Funding
No grant is acknowledged in the PubMed record.
Abstract
5-diphosphoinositol pentakisphosphate (5-IP
Indexed as
ExocytosisAnimalsInositol PhosphatesInsulinMicePhosphorylationReceptors, G-Protein-CoupledSignal TransductionSynaptotagmins1-diphosphoinositol pentakisphosphateInositol PhosphatesInsulinReceptors, G-Protein-CoupledSynaptotagmins
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.