Evidence map›Paper›PMID 34663935›Full record

ReviewExperimental & molecular medicine2021

Biobanking of human gut organoids for translational research.

Francesca Perrone, Matthias Zilbauer

Open access · goldAbstract readReview
In one paragraph

Review in Experimental & molecular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 46 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Bioprinted Organoids: An Innovative Engine in Biomedicine.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Potential Use of Organoids in Regenerative Medicine.Tissue engineering and regenerative medicine · 2024
    Review
  11. Review
  12. Review
  13. Advances in the study of gastric organoids as disease models.World journal of gastrointestinal oncology · 2024
    Review
  14. Review
  15. Article
  16. Review
  17. Review
  18. Review
  19. A Roadmap for the Human Gut Cell Atlas.Nature reviews. Gastroenterology & hepatology · 2023
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Francesca PerroneDepartment of Paediatrics, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.
Matthias ZilbauerDepartment of Paediatrics, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK. mz304@cam.ac.uk.ORCID http://orcid.org/0000-0002-7272-0547
University of Cambridge · GBWellcome/MRC Cambridge Stem Cell Institute · GB

Funding

Medical Research Council
6 · The paper itself

Abstract

The development of human organoid culture models has led to unprecedented opportunities to generate self-organizing, three-dimensional miniature organs that closely mimic in vivo conditions. The ability to expand, culture, and bank such organoids now provide researchers with the opportunity to generate next-generation living biobanks, which will substantially contribute to translational research in a wide range of areas, including drug discovery and testing, regenerative medicine as well as the development of a personalized treatment approach. However, compared to traditional tissue repositories, the generation of a living organoid biobank requires a much higher level of coordination, additional resources, and scientific expertise. In this short review, we discuss the opportunities and challenges associated with the generation of a living organoid biobank. Focusing on human intestinal organoids, we highlight some of the key aspects that need to be considered and provide an outlook for future development in this exciting field.

Indexed as

OrganoidsTranslational Research, BiomedicalBiological Specimen BanksDrug DiscoveryHumansRegenerative Medicine

Identifiers

PMID34663935
PMCPMC8569164
OpenAlexW3206674739

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.