ArticleNature communications2021
Conformer-specific polar cycloaddition of dibromobutadiene with trapped propene ions.
Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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Who cites it
9 citing papers in PubMed.
- Site- and conformer-specific reaction dynamics of glycine with the hydroxyl radical.Communications chemistry · 2025Article
- Unraveling the Conformational and Electronic Landscape of 3‑Pyridinecarboxaldehyde: A Spectroscopic Journey through Conformer-Specific Ionization.ACS physical chemistry Au · 2025Article
- The Diels-Alder Reaction as a Mechanistic Probe for Vibrational Strong Coupling.Angewandte Chemie (International ed. in English) · 2025Article
- Synthesis of thiopyran derivativesRSC advances · 2025Review
- Collisional alignment and molecular rotation control the chemi-ionization of individual conformers of hydroquinone with metastable neon.Nature chemistry · 2024Article
- Isomeric and rotational effects in the chemi-ionisation of 1,2-dibromoethene with metastable neon atoms.Faraday discussions · 2024Article
- Spatial and Temporal Detection of Ions Ejected from Coulomb Crystals.The journal of physical chemistry. A · 2024Article
- Conformational and state-specific effects in reactions of 2,3-dibromobutadiene with Coulomb-crystallized calcium ions.Physical chemistry chemical physics : PCCP · 2023Article
- The topology of the reaction stereo-dynamics in chemi-ionizations.Communications chemistry · 2023Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Diels-Alder cycloadditions are efficient routes for the synthesis of cyclic organic compounds. There has been a long-standing discussion whether these reactions proceed via stepwise or concerted mechanisms. Here, we adopt an experimental approach to explore the mechanism of the model polar cycloaddition of 2,3-dibromo-1,3-butadiene with propene ions by probing its conformational specificities in the entrance channel under single-collision conditions in the gas phase. Combining a conformationally controlled molecular beam with trapped ions, we find that both conformers of the diene, gauche and s-trans, are reactive with capture-limited reaction rates. Aided by quantum-chemical and quantum-capture calculations, this finding is rationalised by a simultaneous competition of concerted and stepwise reaction pathways, revealing an interesting mechanistic borderline case.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.