ArticleNature communications2021
Noradrenergic arousal after encoding reverses the course of systems consolidation in humans.
Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Mood-congruent memory revisited.Psychological review · 2023Pooled it
- Alpha-2 Adrenoreceptor Antagonist Yohimbine Potentiates Consolidation of Conditioned Fear.The international journal of neuropsychopharmacology · 2022Trial
- Affective schemas: Acquisition, updating, and inference.Emotion (Washington, D.C.) · 2026Article
- Posttraining noradrenergic stimulation maintains hippocampal engram reactivation and episodic-like specificity of remote memory.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025Article
- Noradrenergic activation of the basolateral amygdala facilitates memory specificity for similar events experienced close in time.Nature neuroscience · 2025Article
- Memory Boost for Recurring Emotional Events Is Driven by Initial Amygdala Response Promoting Stable Neocortical Patterns across Repetitions.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Stress Molecular Signaling in Interaction With Cognition.Biological psychiatry · 2025Review
- Reactivation and consolidation of memory traces during post-encoding rest across the adult lifespan.Annals of clinical and translational neurology · 2025Review
- Article
- Review
- Opposing effects of pre-encoding stress on neural substrates of item and emotional contextual source memory retrieval.Neurobiology of stress · 2024Article
- Post-retrieval stress impairs subsequent memory depending on hippocampal memory trace reinstatement during reactivation.Science advances · 2024Article
- Overnight neuronal plasticity and adaptation to emotional distress.Nature reviews. Neuroscience · 2024Review
- Time-dependent memory transformation in hippocampus and neocortex is semantic in nature.Nature communications · 2023Article
- Impaired Cholesterol Metabolism, Neurons, and Neuropsychiatric Disorders.Experimental neurobiology · 2023Review
- The impact of post-encoding alcohol consumption on episodic memory recall and remember-know responses in heavy drinkers.Frontiers in psychology · 2023Article
- Knowledge mapping of the relationship between norepinephrine and memory: a bibliometric analysis.Frontiers in endocrinology · 2023Article
- Noradrenergic arousal after encoding reverses the course of systems consolidation in humans.Nature communications · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
It is commonly assumed that episodic memories undergo a time-dependent systems consolidation process, during which hippocampus-dependent memories eventually become reliant on neocortical areas. Here we show that systems consolidation dynamics can be experimentally manipulated and even reversed. We combined a single pharmacological elevation of post-encoding noradrenergic activity through the α
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.