ArticleJournal of orthopaedic surgery and research2021
Poor outcomes of revision total knee arthroplasty in patients with septic loosening compared to patients with aseptic loosening.
Article in Journal of orthopaedic surgery and research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- A systematic review and meta-analysis comparing outcomes following total knee arthroplasty for rheumatoid arthritis versus for osteoarthritis.BMC musculoskeletal disorders · 2023Pooled it
- High early complication risk but low risk of re-revision beyond 5 years following revision knee arthroplasty in the elderly: An analysis of 2833 cases using real-world data from an international database.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2026Article
- Reconstructive Arthroplasty for Malignant Bone Tumors of the Knee-A Single-Center Experience of Functionality and Quality of Life.Journal of clinical medicine · 2025Article
- Etiology and prosthesis model have no influence in the functional outcomes of total knee arthroplasty revision surgery at five years.Journal of clinical orthopaedics and trauma · 2024Article
- "Is every revision the same?" definition of complexity in knee revision surgery.International orthopaedics · 2024Article
- Midterm results of modular hinge total knee arthroplasty using cementless osseointegrating stems: low fixation associated complications and good functional outcome in primary and revision knee arthroplasty.Archives of orthopaedic and trauma surgery · 2024Article
- Long-term outcomes of primary total knee arthroplasty in patients with hepatitis B virus infection.Bone & joint open · 2022Article
- Which Total Knee Arthroplasty Revisions Do Not Improve Patient-Reported Outcomes?JB & JS open accessArticle
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe purpose of this study was to compare the functional outcomes, activity levels, mortalities, implant survival rates, and complications in revision total knee arthroplasty (TKA) of patients with septic loosening with those in patients with aseptic loosening over a minimum 10-year follow-up period.
methodsA cohort of 78 patients (36 septic loosening and 42 aseptic loosening) was selected between January 2008 and December 2009. The functional outcomes, activity levels, mortalities, implant survival rates, and complications of revision TKA in patients with septic and aseptic loosening were compared.
resultsThe mean Knee Society knee scores in the septic and aseptic groups improved from 36.7 and 37.4 preoperatively to 65.3 and 76.8 points at the final follow-up, respectively (p < 0.05). Outdoor ambulatory patients at the final follow-up included 20 of 29 (69.0%) patients in the septic group and 35 of 39 (89.7%) patients in the aseptic group (p < 0.05). The cumulative mortality rates in the septic and aseptic groups were 19.4% (7/36) and 7.1% (3/42) (p = 0.102) at final follow-up, respectively. Kaplan-Meier survivorship analysis with re-revision of either component as an endpoint in the septic and aseptic groups estimated 86.5% and 95.5% chance of survival for 10 years, respectively.
conclusionsRevision TKA in patients with septic loosening had worse functional outcomes and higher mortality over a minimum 10-year follow-up period compared with that in patients with aseptic loosening. LEVEL OF EVIDENCE: IV.
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